Sentences with phrase «prematurely aging mice»

The cardiovascular system, which often fails and causes early death in these prematurely aging mice, also showed improvements in structure and function.

Partial reprogramming of cells within prematurely aging mice's bodies extended the rodents» average life span from 18 weeks to 24 weeks, researchers report December 15 in Cell.

Not exact matches

The researchers then confirmed that the number of singly paired chromosomes — also called univalents — was higher in older mouse and even human egg cells, indicating that age - related segregation errors could be tracked back to increased numbers of prematurely separated chromosome pairs.

Ret is not an unknown factor for the Martinsried - based neurobiologists: «We already succeeded in demonstrating a few years ago in mice that neurons without the Ret receptor die prematurely and in greater numbers with increasing age,» says Klein.

One substance in the blood of old mice, a protein called Beta ‑ 2 ‑ microglobulin, or B2M, seemed to prematurely age the young ones, Villeda and colleagues reported last year in Nature Medicine (SN: 8/8/15, p. 10).

Old blood can prematurely age the brains of young mice, and scientists may now be closer to understanding how.

But the younger mice age prematurely.

(6) Moreover, subcutaneous adipose of prematurely - aged transgenic mice exhibited high levels of staining for the senescence marker senescence - associated - β - galactosidase (SAβ - gal) and expressed high levels of several established markers of senescence, including p21, p19, interleukin - 6, (insulin - like growth factor binding protein - 2 (Igfbp2), and Pai - 1; primary BubR1H / H; INK - ATTAC mouse embryonic fibroblasts forced artificially into senescence by oncogenic Ras or serial passage exhibited a subpopulation that was both GFP + and stained positively SAβ - gal.

Professor Tarnopolsky led a study of mice, some of which were genetically engineered to age prematurely.