Sentences with phrase «prescribed valproate»
The study of 6,671 individuals found lower rates of self - harm and unintentional injuries among those patients taking lithium compared with those prescribed valproate, olanzapine or quetiapine.
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The drug — a mood stabilizer called valproate — is commonly prescribed to treat bipolar disorder and schizophrenia, though its mechanism of action is poorly understood and only some patients respond to the treatment.
Valproate, one of the most commonly prescribed antiepileptic medications, has been associated in the past with birth defects and developmental problems.
Joseph F. Hayes, M.Sc., M.B.Ch.B., of University College London, England, and coauthors compared rates of self - harm, unintentional injury and suicide deaths in patients prescribed lithium, valproate sodium, olanzapine or quetiapine using a large database of electronic health records in the United Kingdom.
To compare lithium against newer medications, Hayes and his colleagues collected medical data on nearly 6,700 people diagnosed as bipolar and prescribed only one of the drugs — lithium, valproate, olanzapine or quetiapine.