Sentences with phrase «presence of cell surface markers»
ES cells can be described based on a characteristic morphology, the presence of cell surface markers such as SSEA - 1 and Pecam1, or the expression of the key transcription factors such as Oct4, Sox2, Nanog, and a number of ES cell - specific transcripts (ECATs)[4]--[6].
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A stem cell is generally characterized by the presence of various proteins — or cell markers — on its outer surface.
(A) Flow cytometry of two independent HV clones (HV 5.1 and HV 16.1) cultured either under self - renewing conditions or in the absence of LIF show the presence of a subpopulation of cells positive for Venus and / or the ES cell surface marker SSEA - 1.
An inherent problem with this approach is that the presence of specific cell surface markers does not directly reflect the transcriptional state of a cell.
The success of marker - based approaches for dissecting haematopoiesis in mouse and human is reliant on the presence of well - defined cell surface markers specific for diverse progenitor populations.