Sentences with phrase «present on cancer cells»

By contrast, the neoantigen vaccine is custom - made for each patient using antigens produced by mutations unique to the patient's cancer and only present on cancer cells, thus bypassing the nature immune tolerance process.

Not exact matches

Dr. Weiss» study of pembrolizumab was presented during a session on small cell lung cancer when the theme of the conference was Science Drives Lung Cancer Advcancer when the theme of the conference was Science Drives Lung Cancer AdvCancer Advances.

When the cancer microRNAs were present and able to turn the DNA circuit on, cells were unable to grow.

One postdoc presents data on her efforts to develop an organoid model for small - cell lung cancer; another reports progress on culturing hormone - secreting organoids from human gut tissue.

A pancreatic cancer vaccine could be made of whole pancreatic cancer cells, treated so they can't replicate, but modified to present certain molecules on the surface of those cells.

A similar idea involves injecting cancer patients with strains of different bacteria that have been genetically modified to present antigens found on pancreatic cancer cells.

Researchers have discovered that a marker found on aggressive prostate cancer cells could also be used as a way to guide treatments to the cancer, according to new research presented at the National Cancer Research Institute (NCRI) Cancer Conference in Livecancer cells could also be used as a way to guide treatments to the cancer, according to new research presented at the National Cancer Research Institute (NCRI) Cancer Conference in Livecancer, according to new research presented at the National Cancer Research Institute (NCRI) Cancer Conference in LiveCancer Research Institute (NCRI) Cancer Conference in LiveCancer Conference in Liverpool.

The study also presents a new model that explains how growth promoting genes could be epigenetically turned on and growth inhibiting genes could be epigenetically turned off in cancer cell formation.

One of the immunotherapeutic approaches that has been explored thus far relies on the use of monoclonal antibodies that specifically target a protein present on the surface of prostate cancer cells called prostate specific membrane antigen (PSMA) to elicit an anti-tumor immune response and control the cancer.

This study, which will be published Oct. 24 in eLife, and two other new Northwestern studies in Oncotarget and Cell Cycle by the Peter group, describe the discovery of the assassin molecules present in multiple human genes and their powerful effect on cancer in mice.

Neoantigens are molecules on cell's surfaces that are produced by DNA mutations that are present in cancer cells but not in normal cells, making neoantigens ideal targets for immune therapy against cancer, say the scientists.

Since then, other checkpoint inhibitors have been developed and commercialised to block a T - cell receptor called PD - 1 or its ligand PD - L1, present on some normal cells as well as cancer cells.

Once taken up by antigen - presenting cells, which help focus the immune system on an invader, the vaccine releases a factor that heightens their attention specifically to the cancer - promoting protein E7, a so - called oncoprotein that not only enables the human papillomavirus to multiply, but potentially cervical cancer cells to do the same.

We also found that the EphB4 receptor expressed on the surface of breast cancer cells can promote tumor xenograft growth by enhancing blood vessel formation through interactions with its preferred ligand, ephrin - B2, present in tumor endothelial cells.

Recently she characterized anti-tumor effects of a unique human CD4 + helper T - cell subset that directly recognizes the cytoplasmic tumor antigen, NY - ESO - 1, presented by MHC class II on cancer cells.

By changing the mouse model they use to study how the immune system responds to cancer, a team of researchers hopes to shift the focus for one form of cancer immunotherapy back to the standard approach — relying on antigen - presenting dendritic cells — and away from the current upstart, macrophages.

Depending on their location in the genome and the proportion of cells they are present in, these mosaic mutations can cause a wide range of genetic disease syndromes and predispose carriers to cancer.

Cancer cell metabolism is dependent upon methionine being present in the diet; whereas normal cells can grow on a methionine - free

Cancer cell metabolism is dependent upon methionine being present in the diet; whereas normal cells can grow on a methionine - free diet feeding off other sulfur - containing amino acids.

Their sense of smell is so great that they can pick up on the distinctive smell of cancer cells, and some have been trained to detect extremely subtle scents the human body gives off when cancer is present.

The difference between the two is based on the type of cancer cells present.