Concomitant PLK4OE and p53 deletion (PLK4OE / p53cKO) rescued the differentiation defects, but did not
prevent the apoptosis of PLK4OE cells.
Receptor interacting protein kinase 1 (RIPK1) has important kinase - dependent and kinase - independent scaffolding functions that activate or
prevent apoptosis or necroptosis in a cell context — dependent manner.
«What was especially surprising and exciting was that a non-chemical procedure can
prevent apoptosis in stem cells therapy for spinal cord injury patients,» Fan said.
ABT - 737 targets proteins known as B - cell lymphoma 2 (Bcl - 2) and Bcl - xL, which
prevent apoptosis, a form of cell suicide, in cancer cells.
The results were that BES enhanced cell survival and
prevented the apoptosis of NPCs caused by growth factor deprivation.
Brca1 is required for embryonic development of the mouse cerebral cortex to normal size by
preventing apoptosis of early neural progenitors.
Supplementation of creatine and ribose
prevents apoptosis and right ventricle hypertrophy in hypoxic hearts.
Part III: N - Acetylcysteine, Alpha - Lipoic Acid, L - Glutamine, and L - Carnitine Alternative Medicine Review 2000 (Aug); 5 (4): 290 — 305 ~ FULL TEXT The role of antioxidants in
preventing apoptosis and viral activation in HIV is well documented.
Not exact matches
The main function of the c - FLIP protein is to
prevent the TNF - related
apoptosis - inducing ligand (TRAIL) from killing cells.
By invigorating the mitochondria, SIRT3 and SIRT4 extend the life of cells, by
preventing flagging mitochondria from developing tiny holes (or pores) in their membranes that allow proteins that trigger
apoptosis, or cell death, to seep out into the rest of the cell.
Survivin belongs to a class of proteins that
prevent cells from self - destructing, a process known as
apoptosis.
The drug, known as HRX9, works by
preventing the cancer cells from avoiding
apoptosis — the natural process by which unhealthy and damaged cells close themselves down and die.
«These findings suggest that BES may thus be used as a strategy to improve cell survival and
prevent cell
apoptosis in stem cell - based transplantation therapies,» Fan explained.
In many cancers, p53 is
prevented from triggering
apoptosis by its attachment to BCL - xL.
Histone deacetylase inhibitors
prevent p53 - dependent and p53 - independent Bax - mediated neuronal
apoptosis through two distinct mechanisms.
Ionizing radiation is a potent DNA damaging agent that interacts with cellular DNA and induces lesions in the irradiated cells and
prevents cell proliferation and induces cell death by
apoptosis or necrosis depending on the radiation dose.
Systemic delivery of TNF - related
apoptosis - inducing ligand (TRAIL) elevates levels of tissue inhibitor of metalloproteinase - 1 (TIMP - 1) and
prevents type 1 diabetes in nonobese diabetic mice.
Oncogenes — whose protein products, when activated, cause uncontrolled cell proliferation or
prevent cells from undergoing
apoptosis.
Then Hu expressed lincRNA - EPS in maturing red blood cells and grew these cells in the absence of the hormone erythropoietin, which normally
prevents the blood cell progenitors from undergoing
apoptosis.
Moreover, LA
prevented the prostatic hyperplasia induced by testosterone in rats, triggered
apoptosis in colon cancer cells through oxidative stress and improved the sensitization of the EGFR inhibitor cetuximab in KRAS / BRAF mutated colorectal cancer cells.
Chlorella has anticancer properties,
preventing the growth of cancerous cells by inducing
apoptosis, or cell death.
They also act aggressively against cancer by
preventing cancer cell proliferation, inducing
apoptosis — or cancer cell «suicide» — and inhibiting the formation of new blood vessels that nourish tumor growth.
Upregulation of lymphocyte
apoptosis as a strategy for
preventing and treating autoimmune disorders: a role for whole - food vegan diets, fish oil and dopamine agonists
It rebalances acid / alkaline in the system and may help
prevent other cancers by inducing
apoptosis in human skin, thyroid, gastric, liver, colon, cervical and prostate cancer cells.
In addition to its antioxidant properties, vitamin C has been shown to reduce monocyte adherence to the endothelium, improve endothelium - dependent nitric oxide production and vasodilation, and reduce vascular smooth - muscle - cell
apoptosis, which
prevents plaque instability in atherosclerosis [2,56].