Sentences with phrase «prevent misfolding»

One study presented by Dr. Donald Weaver, from the Krembil Research Institute of the University of Toronto, found that an extract of maple syrup may help prevent the misfolding and clumping of two types of proteins found in brain cells - beta amyloid and tau peptide.

Dr. Kay continues, «Larger, more complex proteins often rely on chaperones to prevent misfolding and produce functional protein.

Building on this work, Ming, Darrell Cole Cerrato and colleagues at the University of South Florida wanted to find out if betanin, a beet compound used in commercial dyes that readily binds to metals, could block the effects of copper on beta - amyloid and, in turn, prevent the misfolding of these peptides and the oxidation of neurons.

«Less oxidation could prevent misfolding to a certain degree, perhaps even to the point that it slows the aggregation of beta - amyloid peptides, which is believed to be the ultimate cause of Alzheimer's.»

This may prevent the misfolding that accompanies ageing, which can lead to the formation of protein clumps seen in Alzheimer's (Nature, DOI: 10.1038 / nature09873).

Not exact matches

A COMMON dye used to identify the tangles of proteins that accompany ageing also helps to prevent protein misfolding — one of the hallmarks of Alzheimer's disease.

Interferon - inducible protein 6 - 16 (IFI 6 - 16), a protein not previously known to be associated with other misfolding diseases but that was uniquely found misfolded in the urine of women with preeclampsia, is known to help prevent cell death and, in breast cancer cells, is responsible for resistance to treatment.

«It's conceivable down the road that there could be ways to prevent alpha - synuclein misfolding, if you can make the diagnosis early.»

Metabolites derived from the microbiome block protein misfolding in test tubes and prevent neurodegeneration in a fly model of a disease related to Parkinson's, hinting that gut - derived metabolites may hold therapeutic promise (Lap Ho, abstract 573.23, see attached summary).

Changes in these activities caused by mutations or other processes can cause protein misfolding or prevent protein degradation, affect the function and distribution of tau, and lead to degenerative diseases.