Therapies that
prevent tumor blood vessel growth are often used in clinics to fight cancer — but they are only effective in a particular subset of patients.
Not exact matches
«What we may be looking at,» he adds, «is a future way to
prevent metastasis to many organs simultaneously» using drugs that make
tumor cells let go of the
blood vessels they cling to.
«If we could
prevent development of the new
blood vessels in the cancer tissue driven by these signals,
tumor growth and metastasis can be slowed down or
prevented.»
One goal of drug designers has been to
prevent tumors from making new
blood vessels, a process known as angiogenesis.
Eventually, it could form the basis for a treatment to
prevent a
tumor from attracting new
blood vessels.
Some analyses have questioned whether the passive targeting strategy, which depends on the circulating medication slipping through the unique apertures of a
tumor, is effective, noting that the
blood vessels that spring up around
tumors may not be as porous as originally thought, and therefore may
prevent large quantities of the nanodrug from reaching its target.
More than 90 percent of patients with either high nm23, a protein that
prevents the cancer from spreading, or low angiogenesis, minimal growth of new
blood vessels to supply the budding
tumor, were alive an average of 14 years after treatment, compared to only 70 percent of those with low nm23 or high
vessel density.
5/7/2007 Targeting Sugar on
Blood Vessels May Inhibit Cancer Growth In a study that could point to novel therapies to prevent cancer spread, or metastasis, researchers at the University of California, San Diego (UCSD) School of Medicine have targeted a sugar that supports blood vessel growth in the t
Blood Vessels May Inhibit Cancer Growth In a study that could point to novel therapies to
prevent cancer spread, or metastasis, researchers at the University of California, San Diego (UCSD) School of Medicine have targeted a sugar that supports
blood vessel growth in the t
blood vessel growth in the
tumor.
Van Meirâ $ ™ s laboratory has been studying a
tumor suppressor protein called BAI1 (brain angiogenesis inhibitor 1), which
prevents tumor and
blood vessel growth.
Red clover (Trifolium pratense) contains genistein, an anticancer compound that
prevents new
blood vessels from forming with in a
tumor.
They also act aggressively against cancer by
preventing cancer cell proliferation, inducing apoptosis — or cancer cell «suicide» — and inhibiting the formation of new
blood vessels that nourish
tumor growth.
And, although this effect may help to
prevent heart attacks and other forms of heart disease, it may have the potential to promote cancer as well by increasing the growth of
blood vessels in cancerous
tumors.