Sentences with phrase «prevents cell proliferation»

Ionizing radiation is a potent DNA damaging agent that interacts with cellular DNA and induces lesions in the irradiated cells and prevents cell proliferation and induces cell death by apoptosis or necrosis depending on the radiation dose.

Not exact matches

In summary, less Cdh1 prevents the normal function of APC / C, which eventually inhibits the degradation of PAX3, potentially leading to unregulated cell proliferation and cancer (melanoma in skin cell models).

In most normal adult cells, however, telomerase is switched off almost entirely to prevent the dangers of runaway cell proliferation.

A new potential therapeutic agent, diphenyleneiodonium chloride (DPI), effectively switches off cancer stem cells, preventing their proliferation, researchers report.

The laboratory of Marcos Malumbres, who is head of the Spanish National Cancer Research Centre's (CNIO) Cell Division & Cancer Group, working alongside Isabel Fariñas» team from the University of Valencia, shows, in a study published today in the journal Nature Communications, how in mice the elimination of the Cdh1 protein — a sub-unit of the APC / C complex, involved in the control of cell division — prevents cellular proliferation of rapidly dividing ceCell Division & Cancer Group, working alongside Isabel Fariñas» team from the University of Valencia, shows, in a study published today in the journal Nature Communications, how in mice the elimination of the Cdh1 protein — a sub-unit of the APC / C complex, involved in the control of cell division — prevents cellular proliferation of rapidly dividing cecell division — prevents cellular proliferation of rapidly dividing cells.

In cell cultures and in mice LPA prevented signaling within cells, the appearance of molecules associated with T - cell activation, and proliferation of the T cells.

«We show for the first time how HIV / AIDS inhibits proliferation of neural stem cells and prevents the formation of new nerve cells in the adult brain,» said Dr. Stuart Lipton, Director of Burnham's Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research.

Abstract: In response to DNA lesions, human cells activate checkpoint pathways to repair DNA damage and prevent proliferation of genetically unstable cells.

Mutations in the PTEN gene prevent the proper regulation of cell proliferation.

Social isolation prevents exercise - induced proliferation of hippocampal progenitor cells in female rats.

The authors speculate that treatment of the mice with broad - spectrum antibiotics would kill multiple pathogens in the gut and alter the biome so that the proliferation of the tuft cells would be prevented.

Oncogenes — whose protein products, when activated, cause uncontrolled cell proliferation or prevent cells from undergoing apoptosis.

We know that some of these cancer - specific epigenetic changes work like molecular switches that turn off specific caretaker genes, whose function is to safeguard the genome and prevent inappropriate proliferation, to facilitate cancer cell formation and growth.

[21] Furthermore, they have no anti-inflammatory effects, nor do they have any effect on mitotic catastrophe, an important step in preventing proliferation of some cancerous cells.

Both antioxidant compounds work reducing the proliferation of reactive oxygen species in cells, preventing mutations and dead due to oxidative stress.

In fact, in a 2004 study published in the Journal of Agricultural and Food Chemistry, it was concluded that chlorogenic acid antioxidants may prevent the proliferation of four kinds of cancer cells, suggesting green coffee bean extract may even help to prevent cancer.

They also act aggressively against cancer by preventing cancer cell proliferation, inducing apoptosis — or cancer cell «suicide» — and inhibiting the formation of new blood vessels that nourish tumor growth.

They also prevent LDL oxidation, and inhibit SMC proliferation and adhesion of inflammatory blood cells to vessel walls.