Knowing the structure of survivin «doesn't clear up the controversy» about how
it prevents cell suicide, says biochemist Guy Salvesen of the Burnham Institute in La Jolla.
Not exact matches
Studies of the lens of the eye not only could reveal ways to
prevent cataracts but also might illuminate the biology of Alzheimer's, Parkinson's and other diseases in which
cells commit
suicide
They also tested other chemicals known to
prevent the other two forms of cellular
suicide, but only CGP3466B protected mouse nerve
cells in the brain from death by cocaine.
Day 0: Around 9,000 stem
cells are transferred into V - shaped wells and suspended in a cocktail of vitamins, amino acids and (for the first six days) Y - 27632, a chemical to
prevent the stem
cells from committing
suicide.
ABT - 737 targets proteins known as B -
cell lymphoma 2 (Bcl - 2) and Bcl - xL, which
prevent apoptosis, a form of
cell suicide, in cancer
cells.
The next step would be immunosuppressive therapy, which could slow down viral replication by limiting the T
cell activation and
prevent the CD4 + T
cells from committing
suicide.
January 23, 1997 How
cells prevent suicide Researchers have shown that a mysterious protein, crucial to the survival of
cells throughout the body, is able to form a channel through the internal membranes of
cells, and thus may perform the vital function of selectively passing atoms or electrically charged ions between the
cell's compartments.
Previous research from the Greene laboratory revealed that the main cause of
cell death in HIV involves a programmed
cell death pathway called pyroptosis, where the
cells commit a particularly fiery form of
suicide in self - defense to
prevent the spread of the virus.
They also act aggressively against cancer by
preventing cancer
cell proliferation, inducing apoptosis — or cancer
cell «
suicide» — and inhibiting the formation of new blood vessels that nourish tumor growth.