Sentences with phrase «prevents telomeres»

In that time, she has uncovered key elements in the biological machinery that prevents telomeres from shortening with each cell division.

So, if looking youthful and full of energy is your main priority and you want to prevent the telomeres of shortening too fast and too soon, you know what to do.

Not exact matches

Telomeres provide protection to chromosomes during the replication process to prevent the loss of DNA strands.

The boosted genes had three main beneficial effects: improving the efficiency of mitochondria, the powerhouse of cells; boosting insulin production, which improves control of blood sugar; and preventing the depletion of telomeres, caps on chromosomes that help to keep DNA stable and so prevent cells wearing out and ageing.

The telomere prevents this problem by employing a different mechanism to synthesize DNA at this point, thereby preserving the sequence at the terminal of the chromosome.

Telomeres are protective caps of DNA that prevent damage to the ends of chromosomes.

Telomeres at their ends act as caps to prevent biochemical wear and tear, while the cell choreographs the movement of chromosomes by grabbing hold of its centromere handle.

This widespread lack of the need for telomerase is used by evolution as a key component of our defense against cancer, because having a limit to the size and renewal of telomeres prevents our cells from replicating themselves indefinitely — the crucial hallmark of cancer.

«Indeed, the treatment [with telomerase] significantly prevents mortality from aplastic anemia, and lengthens the telomeres in the blood and in bone marrow,» say the authors.

The shortening of telomeres is a process that occurs naturally in the body each time that a cell divides: during cell division the DNA, which is tightly packaged into chromosomes, must be duplicated but the DNA - copying machinery design itself, prevents the full replication of the ends of the chromosomes.

By specifically targeting the pause signal that prevents restarting DNA repeat synthesis, telomerase enzymatic function can be supercharged to better stave off telomere length reduction, with the potential to rejuvenate aging human adult stem cells.

Building on this «telomere hypothesis,» Geron's big idea was that tinkering with telomerase in cells could stave off their senescence — and prevent aging.

The findings underscore the importance of intervening early to address behavior issues in children to prevent psychosocial stress and shortening of telomeres.

«These studies identify telomeres as a new molecular route implicated in the origin of liver diseases such as cirrhosis, hepatitis or liver cancer, as well as novel therapeutic approaches to prevent and combat them,» concluded the researchers.

Telomeres are DNA regions at the ends of our chromosomes that protect the genetic data of cells, preventing mutations and alterations in the DNA that could potentially cause disease.

As a safeguard, in cells such as egg, sperm, and stem cells, an enzyme called telomerase is responsible for preventing this wear and tear by maintaining telomere length.

It helps to lengthen the telomeres — the proteins and DNA on the ends of chromosomes that prevent dividing chromosomes from fraying — and therefore increases the number of times a cell can divide.

Telomeres — repeating segments of DNA on the ends of chromosomes — are often likened to the plastic caps that prevent shoelaces from fraying.

In the absence of telomerase, telomere shortening limits cellular life span and prevents tumorigenesis.

The team found that deleting the PIN domain from Chp1 prevented heterochromatin formation at the telomeres but didn't affect formation at the centromere.

If this precious enzyme can stave off telomere shortening, then can't it also allow us to prevent death — or even reverse the effects of ageing?

«Indeed, the treatment [with telomerase] significantly prevents mortality from aplastic anaemia, and lengthens the telomeres in the blood and in bone marrow,» say the authors.

His research showed that comprehensive lifestyle changes affect gene expression, «turning on» disease - preventing genes and «turning off» genes that promote cancer and heart disease, as well as the first controlled study showing that these lifestyle changes may begin to reverse aging by lengthening telomeres, the ends of our chromosomes which control aging (in collaboration with Dr. Elizabeth Blackburn, awarded the Nobel Prize in Medicine).

Excess cortisol has been found to shorten the telomeres — the «caps» at the ends of chromosomes that prevent them from tangling with each other.

Telomeres prevent our chromosomes from unraveling and are involved with the replication and stability of DNA molecules.

Meditation may also improve DNA health, preventing premature shortening of our telomeres.

Telomeres are sometimes compared to the plastic ends on shoelaces that prevent them from fraying, only instead of protecting laces they protect our DNA.