«While
previous molecular studies have provided simple snapshots of the gene transcript variations that are associated with the exposure of insects to natural and synthetic chemicals, the genomics approaches used in this study offer a significantly more complex perspective on the biochemical and physiological processes occurring in plant - insect interactions,» Schuler said.
Not exact matches
This date is 20 million years younger than suggestions from
previous studies which used
molecular data from living mammals and assumed a near - constant rate of evolution.
Previous studies showed that we can modify the
molecular structure to make them responsive.
«We found that a particular vaginal bacterium, Gardnerella vaginalis, did not cause infection during exposure to the urinary tract, but it damaged the cells on the surface of the bladder and caused E. coli from a
previous UTI to start multiplying, leading to another bout of disease,» said the
study's senior author, Amanda Lewis, PhD, an assistant professor of
molecular microbiology and of obstetrics and gynecology at Washington University.
Previous studies have suggested that signals from the fetus initiate the birth process, but the precise
molecular mechanisms that lead to labor remained unclear.
The research draws from
previous findings by
molecular biology and genetics professor and
study co-author Mariana Wolfner on how Drosophila females» gene expression, behavior and physiology are changed by mating.
Consistent with most
previous molecular and contemporary morphological
studies (15), they divided modern birds (Neornithes) into Palaeognathae (tinamous and flightless ratites), Galloanseres [Galliformes (landfowl) and Anseriformes (waterfowl)-RSB-, and Neoaves (all other extant birds).
Previous studies have yielded key insights into the structure of the
molecular machine that orchestrates this feat, the chemosensory array.
Previous research, including pioneering work at MD Anderson by this
study's senior author Ignacio Wistuba, M.D., and others, has shown normal - appearing tissue close to lung premalignant and cancer lesions may have tumor - associated
molecular abnormalities.
Dr Margaret O'Hara, from the
Molecular Physics Group and primary investigator on the project, said: «
Previous studies have found potential biomarkers for liver disease, such as isoprene and acetone, but they are not specific enough because they are possible biomarkers for other diseases or can arise from numerous normal metabolic processes.
John Lew, associate professor in the Department of
Molecular, Cellular & Developmental Biology, also participated in this
study, as well as
previous research that has demonstrated cinnamon extract's inhibitory effect on tau aggregation.
A
previous study by Segev at the laboratory for research of
molecular and cellular mechanisms, directed by Prof. Kobi Rosenblum in the Sagol Department of Neurobiology at the University of Haifa, found a connection between a genetic condition known to be a risk factor for sporadic Alzheimer's and premature aging as manifested in ongoing metabolic stress.
To examine the allergy - asthma link,
molecular geneticist Tim Howard and colleagues at the Center for Human Genomics at Wake Forest University in Winston - Salem, North Carolina, took a close look at two genes associated with asthma in
previous studies.
«Such a mosaic anatomical evolution may well be related to the somewhat similar
molecular mosaic evolution between the three species revealed by
previous genetic
studies: each of the chimpanzees species share about 3 percent of genetic traits with humans that are not present in the other chimpanzee species.»
«By
studying the epigenome, we also identified new pathways and
molecular dependencies not apparent in
previous gene expression and mutational
studies,» Northcott said.
«None of the
previous studies had a direct link to any
molecular mechanisms that might be going on,» he says.
Moreover, our
previous study found that regular use of aspirin after diagnosis was associated with longer survival among the 15 % to 30 % of patients with colorectal cancer and with a mutation in phosphatidylinositol -4,5-bisphosphate 3 - kinase, catalytic subunit alpha (PIK3CA [NCBI Entrez Gene 5290]-RRB-, one of the PI3K family genes.30 Markedly improved survival associated with aspirin according to PIK3CA status was also found in an analysis within a separate clinical trial cohort.31 Further investigations for the joint effect of these genes would be helpful to better understand the underlying
molecular mechanisms of aspirin, NSAIDs, and colorectal cancer.
Molecular analyses of the chest sample in a
previous study confirmed the diagnosis of tuberculosis and hinted that TB DNA was extremely well preserved in her body.
In addition,
previous studies done in Wang's lab suggest that BCX, through a different
molecular mechanism, can slow the nicotine - promoted growth of lung tumors and decrease cigarette smoke - induced lung inflammation in animal models.
In a
previous study, Shaw, an associate professor in Salk's
Molecular and Cell Biology Laboratory and researcher in the Institute's new Helmsley Center for Genomic Medicine, demonstrated that cells lacking a normal copy of the LKB1 gene fail to activate AMPK in response to low energy levels.
Our supermatrix expands upon these
previous studies by bringing together sequences from a wide array of
molecular studies, supplemented by new data for four genes, to yield a single primate phylogeny with strong support for the monophyly of most primate genera, families, and higher - level taxa (Primates, Strepsirrhini, Lemuriformes, Lorisiformes, Haplorhini, Tarsiiformes, Simiiformes, Catarrhini, Platyrrhini).