Sentences with phrase «previously uncharacterized»

Here we show that the transcription factor Gata6 controls the identity of the previously uncharacterized sebaceous duct (SD) lineage and identify the Gata6 downstream transcription factor network that specifies a lineage switch between sebocytes and SD cells.
In addition, two abundant previously uncharacterized resistance plasmids were identified.
In a recent paper in the Journal of Biological Chemistry, Franziska Dierck of the University Medical Center of Schleswig - Holstein and colleagues write that they identified a previously uncharacterized z - disc protein named CEFIP upregulated in cardiomyopathy.
The experiments identified a previously uncharacterized gene as essential for intoxication by diphtheria toxin and exotoxin A toxicity, and a cell surface protein needed for cytolethal distending toxin toxicity.
In some cases these seem to represent novel, previously uncharacterized antimicrobial peptides, but many more of these immune - inducible genes are difficult to characterize in the absence of detailed functional studies.
University of Michigan researchers have discovered a new cause of congenital myopathy: a mutation in a previously uncharacterized gene, according...
The sequence uncovers previously uncharacterized genes encoding type IV pili, a surface polysaccharide and iron - acquisition systems.
Through systematic annotation of the resulting movies, we developed a phenotypic profiling system, which shows high correlation with cellular processes and biochemical pathways, thus enabling us to predict new functions for previously uncharacterized genes.
Here, we identified a previously uncharacterized mammalian - specific protein, Beclin 2, which, like Beclin 1, functions in autophagy and interacts with class III PI3K complex components and Bcl - 2.
Yao and Xia say their technique has already revealed a surprisingly critical role for a previously uncharacterized EB1 linker region in tracking microtubule plus - ends in live cells.
Using a specially designed computational tool as a lure, scientists have netted the genomic sequences of almost 12,500 previously uncharacterized viruses from public databases.
We identify previously uncharacterized variants at HERC2 associated with the expression of OCA2.
1) This study reveals a previously uncharacterized role for RNA in beebread / pollen instead of protein, sugar and hormone in royal jelly to influence caste differentiation.
We identify previously uncharacterized genes and variants associated with skin pigmentation in ethnically diverse Africans.
The study, which appears online October 29 in the journal Science Signaling, describes a previously uncharacterized interaction between GRK2 and an enzyme called endothelial nitric oxide synthase (eNOS), in which the two enzymes attempt to block one another's activity, with different outcomes on heart function.
These analyses eventually pointed to a previously uncharacterized gene listed in the database — Gm7325.
It is likely that previously uncharacterized gene products with intriguing effects on behavior will be discovered within these networks.

Not exact matches

Previously, the ocean's numerous planktonic organisms have largely been uncharacterized.
The present study showed that the metabolism of colorectal cancer, distinct from that of pancreatic cancer, depended on genomic alterations, which previously have been uncharacterized, and was not restricted to KRAS mutation alone.
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