Increasing our understanding of the adhesive properties of tumours may also help to develop new treatments to halt the development and spread of
primary brain tumours.»
A tumour that originates within the brain itself is
a primary brain tumour (as opposed to a secondary brain tumour that starts elsewhere in the body but spreads to involve the brain).
Not exact matches
Brain metastases often manifest years after the
primary tumour.
This means that when we rely on analysis of a
primary tumour we may miss mutations in the
brain metastases that we could potentially target and treat effectively with drugs.»
The genetic changes in
brain metastases are independent of any occurring at the same time in the
primary tumour, and in metastases elsewhere in the body, the researchers said.
They concluded that
brain metastases and the
primary tumour share a common genetic ancestor.
The researchers found that, in every patient, the
brain metastasis and
primary tumour shared some of their genetics, but there were also key differences.
«
Brain metastases are a secondary brain tumour, which means they are caused by cancer cells that escape from primary tumours like lung, breast or melanoma, and travel to the brain,» said Mohini Singh, the study's primary author and a PhD candidate in biochemistry at the Michael G. DeGroote School of Medicine at McMa
Brain metastases are a secondary
brain tumour, which means they are caused by cancer cells that escape from primary tumours like lung, breast or melanoma, and travel to the brain,» said Mohini Singh, the study's primary author and a PhD candidate in biochemistry at the Michael G. DeGroote School of Medicine at McMa
brain tumour, which means they are caused by cancer cells that escape from
primary tumours like lung, breast or melanoma, and travel to the
brain,» said Mohini Singh, the study's primary author and a PhD candidate in biochemistry at the Michael G. DeGroote School of Medicine at McMa
brain,» said Mohini Singh, the study's
primary author and a PhD candidate in biochemistry at the Michael G. DeGroote School of Medicine at McMaster.
In addition to
primary tumours which start in the
brain, the secondary or «metastatic»
tumours which originate elsewhere and which migrate to the
brain have been the focus of this new study.
Primary and secondary A
brain tumour is a mass of abnormal cells growing in the
brain.
Primary outcome measures are: carer preparedness measured by the Preparedness for Caregiving Scale28 and carer distress measured by the Distress Thermometer (DT).29, 30 Secondary outcome measures are carer anxiety and depression measured using the Hospital Anxiety and Depression Scale (HADS), 31 carer quality of life measured by the Caregiver Quality of Life Index — Cancer, 32 carer competence measured by the Carer Competence Scale, 33 carer supportive care needs measured by the «Partner and Caregivers Supportive Care Needs Scale ’34 and «
Brain Tumour Specific Supportive Carer Needs for Carers Survey ’35 and health economic cost - consequences measured using a checklist of services used.