Sentences with phrase «primary culture models»

Not exact matches

Parents spend most time with their children, parents create the culture at home, parents are the primary model of godliness, and parents are meant to teach their children.

He is also developing a robust and comprehensive panel of 3 - D cell culture models from patient - derived primary cells that can be used to characterize different disease phenotypes and investigate the chemo - response of cells to novel or known drugs.

Utilizes spontaneous and CRISPR / Cas9 generated mouse lines along with primary cell culture models to look at the molecular intersection between the motor neuron and heart phenotypes in mouse models of Spinal Muscular Atrophy with Respiratory Distress (SMARD).

To address these different topics we are developing relevant animal models that will be used in combination with primary neuronal cultures, rodent brain slices, and brain tissues.

As bioinformatics approaches can only provide partial solutions, a functional analysis pipeline, based on primary (fibroblast) cell cultures, induced Pluripotent Stem cells (iPS) or simple model organisms, is truly essential.

We next sought to determine whether transfection with the miR - 181a inhibitor could also promote neurite growth in primary cultures of E14 VM neurons, which are widely used models of mDA neurons [18].

To begin to test this hypothesis, we first used primary cultures of the E14 rat ventral midbrain (VM), which are an experimental tractable model of mDA neurons that are widely used to study the molecular mechanisms regulating mDA neurite growth [18].

We use a combination of conditional mouse models, primary cell culture (human and mouse), live microscopy, highthroughput genomics and proteomics approaches, and basic molecular biology.

Although this possibility has not yet attracted as much attention as the ideas of cell replacement, personalized medicine and other more direct clinical applications, hESCs are expected to be superior to most commonly used cell - culture models of drug discovery which employ tumor - derived or immortalized cell lines or primary cell culture.

As the inclusion of Aboriginal and Torres Strait Islander Histories and Cultures is a key feature of both the Early Years Learning Framework and the Australian Curriculum, ACER convened a team of Indigenous educators to develop a suite of Little J & Big Cuz resources that model a way for early years educators and primary teachers to bring Aboriginal and Torres Strait Islander perspectives into the classroom as part of daily conversations.

The American model of development remains one of the primary models for many developed and developing industrial cultures from early 20th Century onward that, of course, require a large supply of fossil energy with current infrastructure.