Sentences with phrase «primary human macrophages»

Multispecific monoclonal antibodies bind to primary human macrophages and induce the production of protective chemokines, MIP - 1 and MIP - 2

Not exact matches

While earlier work has reported persistence of HIV in these cells — macrophages — investigators in this work developed a mouse model with an immune system generated from human cells but lacking T cells, which are a primary target of and reservoir for HIV.

Using primary murine bone marrow derived macrophages or human monocyte derived dendritic cells, infected with live or attenuated Chlamydia trachomatis we report that the live organism activates both canonical and non-canonical inflammasomes, but only canonical inflammasomes controlled IL - 1β processing which preceded pyroptosis.