Dr. Sonntag studies this concept on the molecular and cellular level using a translational research approach that integrates the analysis of
human material, such as postmortem brains,
primary cell systems, and
neural cell populations generated from patients» - or healthy individuals» - derived induced pluripotent
stem cells (iPSC), or induced neurons (iNs), in combination with molecular, biochemistry, and lentivirus - mediated gene - engineering technologies.