Sentences with phrase «primary macrophage cells»

Not exact matches

Previous studies have pointed to immune cells called macrophages as the primary immune cell responsible for engulfing and breaking down nerve debris.

His group focused on another type of immune cell known as primary macrophages and their response to live bacterial pathogens.

Expression analysis of macrophage and nonmacrophage cell populations isolated from adipose tissue showed that adipose tissue macrophages are the primary sources of TNF - α and other proinflammatory molecules in adipose tissue.

HIV - 1 triggers WAVE2 phosphorylation in primary CD4 T cells and macrophages, mediating Arp2 / 3 - dependent nuclear migration.

Among the strengths of the study: instead of using just one method to deplete macrophages, the researchers used nine distinct methods to deplete different myeloid cells in various locations, allowing them to pinpoint the most important cell type and its primary location of action.

While earlier work has reported persistence of HIV in these cells — macrophages — investigators in this work developed a mouse model with an immune system generated from human cells but lacking T cells, which are a primary target of and reservoir for HIV.

Using primary murine bone marrow derived macrophages or human monocyte derived dendritic cells, infected with live or attenuated Chlamydia trachomatis we report that the live organism activates both canonical and non-canonical inflammasomes, but only canonical inflammasomes controlled IL - 1β processing which preceded pyroptosis.