Not exact matches
EphA2 spreads cancer by
allowing malignant cells to migrate from the
primary tumor into circulation and eventually to adhere to other tissues.
Glioblastoma is the most lethal form of
primary brain
tumor and leads to death in patients by invading the brain tissue in a process that
allows single cells to move through normal brain tissue, which makes complete surgical removal of the
tumor impossible.
«This was a very difficult study to do, but it
allowed us to take a snapshot of both the
primary tumor, and the
tumor after it had spread, in order to trace its evolution,» said the study's first author Marni Siegel, a graduate student in the UNC MD / PhD program.
Researchers have for the first time developed a technique that coats anticancer drugs in membranes made from a patient's own platelets,
allowing the drugs to last longer in the body and attack both
primary cancer
tumors and the circulating
tumor cells that can cause a cancer to metastasize.
This model recapitulates both the
primary tumor formation and NB cells secondary dissemination and
allowed identifying two major routes of dissemination: peripheral nerves and aorta.
Tumor cells can become dormant in
primary tumors or at any time after metastatic dissemination and can persist in the dormant state for many years,
allowing them to resist treatment.
Tumor cells can become dormant in
primary tumors or at any time after metastatic dissemination and can persist in the dormant state for many years,
allowing tumors to resist treatment.
The goal of a surgical intervention in cancer treatment is to remove or reduce the
primary cancerous
tumor and
allow either chemotherapy or radiation therapy to be more effective.
In
primary tumors — the initial cancerous mutations — Allen and Buckanovich discovered that the protein they identified plays a major role in controlling stem cells which
allow the
tumor to grow.