Sentences with phrase «primates challenge model»

In a next step the efficacy of the vaccine will be tested in a non-human primate challenge model.

Not exact matches

To tackle the challenge of identifying valid biomarkers the group created a multi-organ, computational model that tracks infection dynamics in lungs, blood, and lymph nodes using the extensive non-human primate datasets that were available.

Taken together the findings challenge the «relationship model» theory that, like other primates, chimps engage in grooming on the basis of prior social interactions.

This experiment was conducted to verify the findings in the initial experiment of a hypersensitivity immunopathologic - like reaction after SARS - CoV challenge of vaccinated animals, to determine if a higher dosage of the S protein vaccine (SV) would suppress infection and still exhibit a similar reaction, and whether the original β propiolactone inactivated whole virus vaccine (BPV) that had shown an immunopathologic - like reaction after challenge of vaccinated ferrets and nonhuman primates exhibited a similar immunopathologic reaction in the mouse model [13], [14].

Weiner's team was the first to show that a DNA - based approach could impact an HIV model challenge in nonhuman primates.

More specifically, epigenetic programming of cells would allow them to show more pronounced inflammatory responses when exposed to challenge (Miller et al., 2011a), an effect that has been observed in primate models (Cole et al., 2012), as well as in humans (Irwin and Cole, 2011).