One concern raised by the human brain organoid implants «is that functional integration [of the organoids] into the central nervous system of animals can in
principle alter an animal's behavior or needs,» said bioethicist Jonathan Kimmelman of McGill University in Montreal.
Like the Helsinki Declaration, which forever
altered the ethical landscape of human clinical research, the aim of the Basel Declaration is to bring the scientific community together to further advance the implementation of ethical
principles such as the 3Rs whenever
animals are being used and to call for more trust, transparency and communication on the sensitive topic of
animals in research.