Sentences with phrase «prion infectivity»

Not exact matches

The idea is that scrapie prions might somehow interfere with the infectivity of BSE prions.

Thus, as postulated by the prion hypothesis, the infectivity in mammalian prion disease results from an altered conformation of PrP.

But because the prion hypothesis violates long - standing dogma that a DNA - or RNA - based genome is needed for infectivity, doubters insist that it is not yet proven: A virus or some other as - yet - unidentified microbe, they say, may team up with the prion protein to devastate the nervous system.

Researchers also found that plants can uptake prions from contaminated soil and transport them to different parts of the plant, which can act as a carrier of infectivity.

It is thought that the ability of misfolded prion protein to serve as a nucleus for the misfolding and aggregation of the host prion protein is the key property responsible for prion replication and infectivity (Soto et al., 2006; Soto, 2012).