A diet high in animal protein seems to increase the risk as well, possibly due to blood components in meat, carcinogens created by cooking muscle, chemicals in processed meat,
pro-inflammatory arachidonic acid and iron, harmful bacteria causing inflammation, or even the antibiotics in meat interfering with gut flora.
This could be attributed to a variety of reasons: blood components in meat that degrade into carbon monoxide, carcinogens created by cooking muscle or consuming processed meat,
pro-inflammatory arachidonic acid and iron, huge amounts of bacteria causing inflammation, or even the antibiotics in meat adversely affecting gut flora.
«In such individuals, vegetable oils will be converted to the more
pro-inflammatory arachidonic acid, increasing the risk for chronic inflammation that is implicated in the development of heart disease, and exacerbates cancer.
Not exact matches
It turns out that when applied to skin cells, avenanthramides are able to inhibit the exact same
pro-inflammatory proteins that oatmeal can: IL - 8, TNF - A, NF - kappaB, and
arachidonic acid.
As I illustrated above,
arachidonic acid is processed by the enzyme cyclooxygenase (COX) to produce
pro-inflammatory signaling molecules called eicosanoids, including leukotrienes, prostaglandins, and thromboxanes.
This enzyme is important for creation of the omega - 6 fatty acid called
arachidonic acid (AA), and AA is itself the basic building block for a wide variety of
pro-inflammatory messaging molecules.
The anti-inflammatory properties of Citrus flavonoids are largely due to its affect on
pro-inflammatory mediators, mainly the
arachidonic acid derivatives, prostaglandins E2, F2, and thromboxane A2 [21].
We've known for a long time that
arachidonic acid (found in meats and animal products) is the direct precursor to
pro-inflammatory molecules in the body.
''... increased levels of
pro-inflammatory mediators were also frequently accompanied by a concomitant elevation in anti-inflammatory markers (i.e., adiponectin, Transforming Growth Factor (TGF)- b1, IL - 1 receptor antagonist (IL - 1RA), cortisol, and anti-inflammatory
arachidonic acid - derived compounds...»
These substances prevent the conversion of
arachidonic acid into prostaglandins, thromboxane A2, and prostacyclin, 3 molecules that are largely considered in the scientific community as
pro-inflammatory.