Sentences with phrase «pro-inflammatory signaling cells»

When a person with gluten sensitivity eats gluten (not just wheat, but gliadin, glutenin, and transglutaminase proteins in other grains), the immune system jumps into action, releasing pro-inflammatory signaling cells.

Not exact matches

Hypertonic Saline Primes Activation of the p53 — p21 Signaling Axis in Human Small Airway Epithelial Cells That Prevents Inflammation Induced by Pro-inflammatory Cytokines.

Likewise, many of the same small molecules used by cells to signal to each other as they rout microbes are the ones that whip up unhealthy inflammatory responses, chief among them pro-inflammatory cytokines of the TNF family, which activate T cells and prolong their response.

Josin researchers made two major findings: They identified the mechanisms by which GLP - 1 can induce protective actions on the glomerular (renal) endothelial cells by inhibiting the signaling pathway of Ang II and its pro-inflammatory effect; and demonstrated a dual signaling mechanism by which hyperglycemia, via PKCβ activation, can increase Ang II action and inhibit GLP - 1's protective effects by reducing the expression of GLP - 1 receptors in the glomerular endothelial cells.

Signaling through the CXCR3 - mediated, MyD88 - dependent pathway generates a Th1 - dominant, pro-inflammatory cytokine milieu that recruits mononuclear cells into the submucosa (Fasano, 2011).

Piperine also interferes with inflammatory signaling mechanisms and inhibits pro-inflammatory cytokines, which are small proteins secreted by some cells and linked with a number of degenerative diseases.

Moreover, the idea that the brain was isolated from immune reactions was challenged long ago by insights about microglia cells, a type of macrophage which resides in the brain, engulfs antigens, and produces pro-inflammatory signaling molecules called cytokines.

This accelerates cell senescence, which leads to increased pro-inflammatory and pro-oxidant signaling by the senescence associated secretory phenotype (SASP) response, and induction of mitochondrial dysfunction, thereby propagating DNA damage and senescence to bystander cells.

Most of the proposed mechanisms of actions in these studies involve changes in cell signaling and decreased production of pro-inflammatory cytokines.

The current results suggest that better understanding the way in which mononuclear white blood cell signaling processes are altered, net of effects on individual differences in cell type composition, is promising as a mechanism by which protective parenting influences young adult pro-inflammatory tendencies among African American youth.