Sentences with phrase «process in human cells»

«We have also tested this process in human cells taken from diseased lung tissue, and we see very similar results.»
«This is what we need to find out next, because it could provide some clue as to how we could activate the same process in human cells

Not exact matches

Organovo, a start - up in Los Angeles, is working on a process in which a bioprinter will squirt multiple layers of human tissue cells onto special paper.
It's essentially the same process used in medicine to cultivate human cells and tissues.
While our work has used mouse models because we can study the process in detail this way, we do know that milk cells cross into human babies as well.»
But this process is important because «if the apoptotic cells are not properly cleared... it will affect the cell death activation» in organisms like worms and cause persistent inflammation and autoimmune responses in humans.
Hammer and colleagues Dennis Discher and Frank Bates attempted to scale up this process to make vesicles more than 10 micrometers in diameter — the size of human cells.
Therefore, it is essential that we learn how specific types of chemical modifications normally regulate RNA function in our cells, in order to understand how dysregulation of this process contributes to human disease, says Cristian Bellodi.
The study results were found using mouse embryonic stem cells, which are good cell models for the study of processes seen in human stem cells.
Although de Lange notes that telomere shortening needs further investigation, she says there's now no doubt that telomeres play a critical role in limiting human cell division and that telomerase can reactivate the process.
Adding stem cells from human bone marrow to a broken diabetic bone enhances the repair process, increasing the strength of the newly formed bone, according to a laboratory - based study presented at the European Congress of Endocrinology in Dublin.
The researchers have compared various processes involved in gene expression, such as gene transcription and chromatin modification, and have repeated this in different tissues and cell types from both humans and mice.
There are hundreds of RNA - binding proteins in the human genome that together regulate the processing, turnover and localization of the many thousands of RNA molecules expressed in cells.
But Welte speculates that when internal temperatures do fluctuate in humans, as in the case of fevers, our cells may also need a way to coordinate the protein - building process.
Meanwhile, recent human studies indicate that aging is associated with an increase in somatic mutations in the hematopoietic system, which gives rise to blood cells; these mutations provide a competitive growth advantage to the mutant hematopoietic cells, allowing for their clonal expansion — a process that has been shown to be associated with a greater incidence of atherosclerosis, though specifically how remains unclear.
After «inhaling» E. coli, for instance, the lung attracted human white blood cells to attack and kill the bacteria, a process scientists have long understood but never before witnessed in vitro.
One clinical trial involves the drug CGF166, a one - time gene therapy, which, if proven successful in humans, could regenerate new hair cells within the cochlea that can signal the part of the brain that processes sound.
The researchers observed the effect of the synthetically produced molecule, JK - 31, on the growth and proliferation of a model human breast cancer cell line and found that it effectively blocked the protein cyclin - dependent kinase 1 (CDK1), which plays a key part in the process of the division of cancer cells, and therefore inhibited the proliferation of the cells.
The process, reported in Human Reproduction, utilizes DNA fingerprinting (an assessment of active genes in a given cell) to boost the success rate of IVF and lower the chances of risky multiple births by identifying which of several five - day - old embryos are most likely to result in pregnancy The new method, which will replace unproved alternatives such as choosing embryos based on their shape, is likely to up the success of women becoming pregnant and lower their chances of having multiple births.
The researchers reprogrammed the cells to create induced pluripotent stem cells in an FDA - compliant facility at the Broad Stem Cell Research Center; the use of this facility is an important step in the process as preclinical research moves toward human clinical trials.
In their findings, reported in Nature Physics, the researchers describe a method they developed for growing tiny «brains on chips» from human cells that enabled them to track the physical and biological mechanisms underlying the wrinkling procesIn their findings, reported in Nature Physics, the researchers describe a method they developed for growing tiny «brains on chips» from human cells that enabled them to track the physical and biological mechanisms underlying the wrinkling procesin Nature Physics, the researchers describe a method they developed for growing tiny «brains on chips» from human cells that enabled them to track the physical and biological mechanisms underlying the wrinkling process.
And perhaps surprisingly, these molecules are not produced by human cells, but by a person's gut microbes as they process food in the diet.
ATP (adenosine triphosphate) is the main energy source inside a cell and is considered to be the high energy molecule that drives all life processes in animals and humans.
Tests rely on either expensive equipment for computer - assisted analysis or, in hospitals that can not afford thousands of dollars» worth of machinery, a technician who analyzes sperm cells under a microscope, a process Shafiee says can be subject to human error.
The laboratory process, described in the journal Scientific Reports, entails genetically modifying a line of human embryonic stem cells to become fluorescent upon their differentiation to retinal ganglion cells, and then using that cell line for development of new differentiation methods and characterization of the resulting cells.
Cheng and colleagues did experiments using human cells and identified hnRNPM's role in controlling the processes linked to tumor metastasis.
«We have converted skin cells to stem cells and developed a highly efficient process to convert these stem cells into kidney structures that resemble those found in a normal human kidney.
Programmed cell death, or apoptosis, is a natural process that kills billions of cells in a typical human body each day.
By examining cell processes both in mice and in human cells, the researchers found out why: Re-esterification helps protect a key cell organelle called the endoplasmic reticulum (ER).
In both humans and birds, cells process this gene in a way that produces both a full - length protein and a shorter version of the proteiIn both humans and birds, cells process this gene in a way that produces both a full - length protein and a shorter version of the proteiin a way that produces both a full - length protein and a shorter version of the protein.
Autophagy is the «self - eating» process of consuming the portion of intracellular proteins in the cells of eukaryotes such as yeast, humans and plants.
Autophagy is the «self - eating» process of consuming unwanted elements in the cells of eukaryotes such as yeast, humans and plants.
Further studies showed that very similar genes controlled the process in animal and human cells, and also helped piece together how the genes work together to keep the cell's recycling centers running.
Researchers found 53 existing drugs that may keep the Ebola virus from entering human cells, a key step in the process of infection, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai and the National Institutes of Health (NIH), and published today in the Nature Press journal Emerging Microbes and Infections.
In humans, there are about 100 proteins associated with ubiquitination, the process by which a protein labelled with ubiquitin is removed from the cell by specific cell machinery known as the proteosome.
At the July meeting of the European Society for Human Reproduction and Embryology in Madrid, scientists were horrified — and transfixed — by two presentations: one that explored adding cells to developing embryos and another that outlined a process of growing egg cells from aborted human fetHuman Reproduction and Embryology in Madrid, scientists were horrified — and transfixed — by two presentations: one that explored adding cells to developing embryos and another that outlined a process of growing egg cells from aborted human fethuman fetuses.
The researchers now plan further studies using XR - seq in bacterial cells, as well as in human and other mammalian cells where the process of excision repair is less understood.
Human nerve cells involved in the process are spread throughout the brain.
The next step is to see if the process works and is safe in human cells.
The budding yeast, Saccharomyces cerevisiae, is a prime organism for studying fundamental cellular processes, with the functions of many proteins important in the cell cycle and signaling networks found in human biology having first been discovered in yeast.
The researchers focused on one common epigenetic process known as methylation, in which methyl (CH3) groups attach in various patterns to the genes of human cells.
Each dose is custom - tailored for an individual patient, requiring a complex process in which human cells must be safely ferried across the country, reliably augmented, and soundly returned.
These are some of the fastest migrating cells in the human body, and they are the first responders at damaged locations or areas of infection and begin the process of healing.
«If further studies validate that these processes are critical in human breast cancers,» Koshy notes, «the possibility exists that agents that favorably modify the biophysical properties of the extracellular matrix, or that target the receptors and signaling molecules associated with how cells sense this matrix, could be used as a new avenue for the prevention or treatment of breast cancers.»
Future research Because there are few salivary gland stem cells in the human mouth, the scientists plan to continue using rat salivary glands to refine the process, but eventually hope to use stem cells derived from human bone marrow or umbilical cord blood to regenerate salivary glands for humans.
In the process, the plasma membrane receptor Fas (CD95) is key; this cell receptor occurs in almost all human cells and is involved in programmed cell death (apoptosisIn the process, the plasma membrane receptor Fas (CD95) is key; this cell receptor occurs in almost all human cells and is involved in programmed cell death (apoptosisin almost all human cells and is involved in programmed cell death (apoptosisin programmed cell death (apoptosis).
«Our results are important because the process works in mice and in human muscle cells
In some human cell types, this process is controlled by a family of regulatory proteins called ESRP.
New research from scientists at Huntsman Cancer Institute (HCI) at the University of Utah and collaborators at University of Utah Health (U of U Health) sheds light on the complex process that occurs in the development of human sperm stem cells.
In the Nature papers, the researchers compared gene transcription, chromatin modification and other processes that control gene activity in a wide range of mouse and human tissues and cell typeIn the Nature papers, the researchers compared gene transcription, chromatin modification and other processes that control gene activity in a wide range of mouse and human tissues and cell typein a wide range of mouse and human tissues and cell types.
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