«We have also tested
this process in human cells taken from diseased lung tissue, and we see very similar results.»
«This is what we need to find out next, because it could provide some clue as to how we could activate the same
process in human cells.»
Not exact matches
Organovo, a start - up
in Los Angeles, is working on a
process in which a bioprinter will squirt multiple layers of
human tissue
cells onto special paper.
It's essentially the same
process used
in medicine to cultivate
human cells and tissues.
While our work has used mouse models because we can study the
process in detail this way, we do know that milk
cells cross into
human babies as well.»
But this
process is important because «if the apoptotic
cells are not properly cleared... it will affect the
cell death activation»
in organisms like worms and cause persistent inflammation and autoimmune responses
in humans.
Hammer and colleagues Dennis Discher and Frank Bates attempted to scale up this
process to make vesicles more than 10 micrometers
in diameter — the size of
human cells.
Therefore, it is essential that we learn how specific types of chemical modifications normally regulate RNA function
in our
cells,
in order to understand how dysregulation of this
process contributes to
human disease, says Cristian Bellodi.
The study results were found using mouse embryonic stem
cells, which are good
cell models for the study of
processes seen
in human stem
cells.
Although de Lange notes that telomere shortening needs further investigation, she says there's now no doubt that telomeres play a critical role
in limiting
human cell division and that telomerase can reactivate the
process.
Adding stem
cells from
human bone marrow to a broken diabetic bone enhances the repair
process, increasing the strength of the newly formed bone, according to a laboratory - based study presented at the European Congress of Endocrinology
in Dublin.
The researchers have compared various
processes involved
in gene expression, such as gene transcription and chromatin modification, and have repeated this
in different tissues and
cell types from both
humans and mice.
There are hundreds of RNA - binding proteins
in the
human genome that together regulate the
processing, turnover and localization of the many thousands of RNA molecules expressed
in cells.
But Welte speculates that when internal temperatures do fluctuate
in humans, as
in the case of fevers, our
cells may also need a way to coordinate the protein - building
process.
Meanwhile, recent
human studies indicate that aging is associated with an increase
in somatic mutations
in the hematopoietic system, which gives rise to blood
cells; these mutations provide a competitive growth advantage to the mutant hematopoietic
cells, allowing for their clonal expansion — a
process that has been shown to be associated with a greater incidence of atherosclerosis, though specifically how remains unclear.
After «inhaling» E. coli, for instance, the lung attracted
human white blood
cells to attack and kill the bacteria, a
process scientists have long understood but never before witnessed
in vitro.
One clinical trial involves the drug CGF166, a one - time gene therapy, which, if proven successful
in humans, could regenerate new hair
cells within the cochlea that can signal the part of the brain that
processes sound.
The researchers observed the effect of the synthetically produced molecule, JK - 31, on the growth and proliferation of a model
human breast cancer
cell line and found that it effectively blocked the protein cyclin - dependent kinase 1 (CDK1), which plays a key part
in the
process of the division of cancer
cells, and therefore inhibited the proliferation of the
cells.
The
process, reported
in Human Reproduction, utilizes DNA fingerprinting (an assessment of active genes
in a given
cell) to boost the success rate of IVF and lower the chances of risky multiple births by identifying which of several five - day - old embryos are most likely to result
in pregnancy The new method, which will replace unproved alternatives such as choosing embryos based on their shape, is likely to up the success of women becoming pregnant and lower their chances of having multiple births.
The researchers reprogrammed the
cells to create induced pluripotent stem
cells in an FDA - compliant facility at the Broad Stem
Cell Research Center; the use of this facility is an important step
in the
process as preclinical research moves toward
human clinical trials.
In their findings, reported in Nature Physics, the researchers describe a method they developed for growing tiny «brains on chips» from human cells that enabled them to track the physical and biological mechanisms underlying the wrinkling proces
In their findings, reported
in Nature Physics, the researchers describe a method they developed for growing tiny «brains on chips» from human cells that enabled them to track the physical and biological mechanisms underlying the wrinkling proces
in Nature Physics, the researchers describe a method they developed for growing tiny «brains on chips» from
human cells that enabled them to track the physical and biological mechanisms underlying the wrinkling
process.
And perhaps surprisingly, these molecules are not produced by
human cells, but by a person's gut microbes as they
process food
in the diet.
ATP (adenosine triphosphate) is the main energy source inside a
cell and is considered to be the high energy molecule that drives all life
processes in animals and
humans.
Tests rely on either expensive equipment for computer - assisted analysis or,
in hospitals that can not afford thousands of dollars» worth of machinery, a technician who analyzes sperm
cells under a microscope, a
process Shafiee says can be subject to
human error.
The laboratory
process, described
in the journal Scientific Reports, entails genetically modifying a line of
human embryonic stem
cells to become fluorescent upon their differentiation to retinal ganglion
cells, and then using that
cell line for development of new differentiation methods and characterization of the resulting
cells.
Cheng and colleagues did experiments using
human cells and identified hnRNPM's role
in controlling the
processes linked to tumor metastasis.
«We have converted skin
cells to stem
cells and developed a highly efficient
process to convert these stem
cells into kidney structures that resemble those found
in a normal
human kidney.
Programmed
cell death, or apoptosis, is a natural
process that kills billions of
cells in a typical
human body each day.
By examining
cell processes both
in mice and
in human cells, the researchers found out why: Re-esterification helps protect a key
cell organelle called the endoplasmic reticulum (ER).
In both humans and birds, cells process this gene in a way that produces both a full - length protein and a shorter version of the protei
In both
humans and birds,
cells process this gene
in a way that produces both a full - length protein and a shorter version of the protei
in a way that produces both a full - length protein and a shorter version of the protein.
Autophagy is the «self - eating»
process of consuming the portion of intracellular proteins
in the
cells of eukaryotes such as yeast,
humans and plants.
Autophagy is the «self - eating»
process of consuming unwanted elements
in the
cells of eukaryotes such as yeast,
humans and plants.
Further studies showed that very similar genes controlled the
process in animal and
human cells, and also helped piece together how the genes work together to keep the
cell's recycling centers running.
Researchers found 53 existing drugs that may keep the Ebola virus from entering
human cells, a key step
in the
process of infection, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai and the National Institutes of Health (NIH), and published today
in the Nature Press journal Emerging Microbes and Infections.
In humans, there are about 100 proteins associated with ubiquitination, the
process by which a protein labelled with ubiquitin is removed from the
cell by specific
cell machinery known as the proteosome.
At the July meeting of the European Society for
Human Reproduction and Embryology in Madrid, scientists were horrified — and transfixed — by two presentations: one that explored adding cells to developing embryos and another that outlined a process of growing egg cells from aborted human fet
Human Reproduction and Embryology
in Madrid, scientists were horrified — and transfixed — by two presentations: one that explored adding
cells to developing embryos and another that outlined a
process of growing egg
cells from aborted
human fet
human fetuses.
The researchers now plan further studies using XR - seq
in bacterial
cells, as well as
in human and other mammalian
cells where the
process of excision repair is less understood.
Human nerve
cells involved
in the
process are spread throughout the brain.
The next step is to see if the
process works and is safe
in human cells.
The budding yeast, Saccharomyces cerevisiae, is a prime organism for studying fundamental cellular
processes, with the functions of many proteins important
in the
cell cycle and signaling networks found
in human biology having first been discovered
in yeast.
The researchers focused on one common epigenetic
process known as methylation,
in which methyl (CH3) groups attach
in various patterns to the genes of
human cells.
Each dose is custom - tailored for an individual patient, requiring a complex
process in which
human cells must be safely ferried across the country, reliably augmented, and soundly returned.
These are some of the fastest migrating
cells in the
human body, and they are the first responders at damaged locations or areas of infection and begin the
process of healing.
«If further studies validate that these
processes are critical
in human breast cancers,» Koshy notes, «the possibility exists that agents that favorably modify the biophysical properties of the extracellular matrix, or that target the receptors and signaling molecules associated with how
cells sense this matrix, could be used as a new avenue for the prevention or treatment of breast cancers.»
Future research Because there are few salivary gland stem
cells in the
human mouth, the scientists plan to continue using rat salivary glands to refine the
process, but eventually hope to use stem
cells derived from
human bone marrow or umbilical cord blood to regenerate salivary glands for
humans.
In the process, the plasma membrane receptor Fas (CD95) is key; this cell receptor occurs in almost all human cells and is involved in programmed cell death (apoptosis
In the
process, the plasma membrane receptor Fas (CD95) is key; this
cell receptor occurs
in almost all human cells and is involved in programmed cell death (apoptosis
in almost all
human cells and is involved
in programmed cell death (apoptosis
in programmed
cell death (apoptosis).
«Our results are important because the
process works
in mice and
in human muscle
cells.»
In some
human cell types, this
process is controlled by a family of regulatory proteins called ESRP.
New research from scientists at Huntsman Cancer Institute (HCI) at the University of Utah and collaborators at University of Utah Health (U of U Health) sheds light on the complex
process that occurs
in the development of
human sperm stem
cells.
In the Nature papers, the researchers compared gene transcription, chromatin modification and other processes that control gene activity in a wide range of mouse and human tissues and cell type
In the Nature papers, the researchers compared gene transcription, chromatin modification and other
processes that control gene activity
in a wide range of mouse and human tissues and cell type
in a wide range of mouse and
human tissues and
cell types.