In cells, U1 snRNP plays multiple roles in processing RNA including
the process of alternative splicing, by which one gene can make instructions for two or more proteins.
Not exact matches
The two closely related regulatory genes are active in the normal development
of mammals and govern how RNAs produced from the genes are joined to make final versions
of the encoded protein, a
process called
alternative splicing.
«While gene duplication and
alternative splicing are typically invoked as major mechanisms underpinning protein neofunctionalization, this study suggests that the
process of co-option should be re-evaluated as a potentially important method by which genes can acquire novel functions.»
But parts
of each
of four exons in Dscam can become active separately, at different times — a
process called
alternative splicing.
Alternative splicing is a
process of generating multiple transcripts and protein variants by joining different combinations
of coding segments.
May 07, 2007 Hui Zhu,
of the Eng lab, was featured in Today's Plain Dealer Newspaper in an article highlighting her interest in
alternative splicing, a molecular
process that allows a single gene to produce many different proteins.
Resveratrol, by modulating RNA
processing factor levels, can influence the
alternative splicing of pre-mRNAs.
Lue, whose essay described the regulation
of alternative splicing and how defects in this
process can cause disease, and Mueller, whose essay described examples
of alternatively
spliced proteins coded by the same gene with different functions that act in different cells, will each receive a $ 400 prize, and their science teachers, Dr. Martina Davies and Mrs. Jessica Graham respectively, will each receive a $ 400 grant for genetics materials.
Yang — whose essay described examples
of alternative splicing, a
process by which the same stretch
of DNA and its complementary messenger RNA can be
spliced together in different ways and thus be translated into different proteins — will receive a $ 1000 prize.