Not exact matches
Years of scientific research have shown, however, that this panorama is a construction, enabled
by multiple systems of
neurons specialized for visual
processing.
To do this, the
neurons need to make new proteins — a
process that is thought to be controlled
by hundreds of genes.
The team cemented its finding
by noting the mice's
neurons» ability to undergo long - term potentiation — a type of response to stimulation, which has been implicated in learning
processes — after gene function was restored.
In individuals affected
by SMA, the survival motor
neuron - 1 (SMN1) gene is mutated and lacks the ability to
process a key protein that helps
neurons function.
Last year her lab published evidence that one mechanistic consequence of the disease is a disruption of the
process by which
neurons can recycle and reuse proteins needed for neural control of muscle.
Using a high - resolution analysis of how individual
neurons and their connected brain networks
processed this touch information, designed
by neurocomputational scientist Alberto Mazzoni and physics scientist Anton Spanne, the groups got an unexpected insight into the brain representations of the external world experienced through touch.
The trouble is that recording activity within
neurons is a more delicate
process, which gets disrupted
by the physical movement necessary to trigger place - cell activity.
In individuals affected
by SMA, the spinal motor
neuron - 1 (SMN1) gene is mutated and lacks the ability to
process a key protein that helps muscle
neurons function.
Several years ago researchers measured the older animals» production of new
neurons — a
process that usually diminishes with age — and found it could be rejuvenated
by young blood.
Using a mouse model, the team also demonstrated that two
processes during neurodevelopment are regulated
by the gene: proliferation — the replication of neuronal stem cells that have the potential to become multiple different kinds of cells, including
neurons — and migration — the movement of
neurons to specific locations in the brain during development.
One such drug — known as a Kv3 potassium channel modulator, in development
by U.K. - based Autifony Therapeutics — may help improve
neuron function in the part of the brain responsible for
processing sounds.
Physiologists (especially Leslie G. Ungerleider of the National Institute of Mental Health, Ricardo Gattass of the Federal University of Rio de Janeiro and Charles D. Gilbert of the Rockefeller University) have explored the neural mechanism of this
process by monitoring the manner in which single
neurons in the visual centers respond to objects partially covered
by the blind spot or
by opaque occluders.
«
By permitting rapid neural communication across
neurons encoding different spatial positions, oscillations could contribute to this important perceptual
process.»
Each cell in the image (both
neurons and the support cells known as glia) was color - coded
by hand, a
process that took 150 hours.
A postmortem analysis of human brain tissue, for example, conducted
by Witelson and her colleagues at the Michael G. DeGroote School of Medicine at McMaster, revealed that women's
neurons were 11 percent denser than men's in the prefrontal cortex and in a region of the temporal cortex that is involved with language
processing, comprehension, and memory.
Intriguingly, all seven play a role in cell division, the
process by which immature
neurons multiply in the fetal brain, before migrating to their final location.
This study was designed to better define the
process by which ALS progresses and to explore the role of brain motor
neurons in disease development and progression.
After depletion of synapsin II
by antisense oligonucleotides, rat hippocampal
neurons in culture were unable to consolidate their minor
processes and did not elongate axons.
The researchers also found that activation of ESP1 - responding
neurons in the region of the brain called the hypothalamus enhanced sexual behavior in female mice, even in the absence of actual ESP1,
by using various tools to chemically or optically control neural activities, combined with a
process called the TRAP method, which allows them to selectively manipulate
neurons responding to a particular stimulus.
In a new study published in Science, the laboratory of Sebastian Jessberger, professor in the Brain Research Institute of the University of Zurich, has shown for the first time the
process by which neural stem cells divide and newborn
neurons integrate in the adult mouse hippocampus.
Dr. Goldberg said a smaller scar likely aids the healing
process by isolating the injured
neurons, similar to how isolating a spreading infection can improve recovery.
Each glomerulus — «a ball of axons and dendrites,» according to Albeanu — is a junction where axons from sensory
neurons meet up with and connect, or synapse, with dendrites sent from the next
processing layer in the bulb, populated
by mitral cells.
Dopamine (which is connected to reward
processing, motivation and attention) is one of the brain's primary neurotransmitters, the chemical messengers
by which one
neuron triggers its neighbor to fire a nerve impulse.
«
By adapting an automated
process to
neurons, we were able to go through 800 genes to find one needed for forming synapses — connections — among those cells.»
The authors used functional magnetic resonance imaging to investigate connectivity in two brain networks involved in social
processing: theory of mind (ToM, otherwise known as the mentalizing system, which allows an individual to infer what others are thinking, their beliefs, their intentions) and the mirror
neuron system (MNS, which allows people to understand the meanings and actions of others
by simulating and replicating them).
One is the «spine pruning theory,» supported
by the observation that the frontal brain regions of people with schizophrenia have fewer dendritic spines, the tentacles on the receiving ends of
neurons that
process signals from other cells.
The
neuron pathways activated in the moths were tracked
by inserting a 16 - channel electrode into the moth's antennal lobe, where the moth
processes odor information from its antennae.
This illusion shows that adaptation, the
process by which
neurons in the brain become less responsive to unchanging stimuli, can be simultaneously selective for both color and orientation of edges.
Neurons communicate
by firing action potentials, and if this
process is disrupted then the
neuron can not do its job properly.»
Neurons, or nerve cells, in the brain communicate with each other
by transmitting electric signals, or firing action potentials, through long
processes named axons (which send out signals) and dendrites (which receive signals).
Inner ear stem cells can be converted to auditory
neurons that could reverse deafness, but the
process can also make those cells divide too quickly, posing a cancer risk, according to a study led
by Rutgers University - New Brunswick scientists.
The
process, they suggest, is done
by individual TRN
neurons that act like a «switchboard,» continuously filtering sensory information and shifting more or less attention onto one sense — like sight — while relatively blocking out distracting information from other senses, including sound.
John «Jack» Pettigrew, then a young medical student in Canberra, Australia, noted this fact in the mid 1960s, reasoning that the neural mechanism for stereopsis must entail another set of binocular
neurons, ones that signal retinal disparity
by processing noncorresponding retinal points.
Although memory is still in large part a mystery, scientists think it's a two - step
process: Information first enters a temporary, short - term storage that works
by selectively strengthening connections between some
neurons.
The team also tested its technology's potential
by making a worm lay eggs and
by showing that a particular
neuron processes information from touch - sensing cells.
Three basic mechanisms have been proposed over the years to explain the formation of specific neural circuitry: (1) an elaborate predetermined program encoded genetically in each
neuron that unfolds according to rigid and unmodifiable rules, (2) a random
process of trial and error in which growing nerve fibers that make the right connections are consolidated and those that fail are reabsorbed and (3) a general program of circuit formation that is brought to completion
by an interplay between genetic and extrinsic factors.
The basic
process by which signals pass through the brain involves neurotransmitters, which are carried inside the synaptic vesicles, being passed across synapses — the junctions between
neurons.
Researchers believe that this inhibitory
process caused
by an overabundance of alpha - synuclein is what occurs in the early stages of Parkinson's disease, before morphological changes such as the loss of function and death of
neurons begins.
A new study authored
by Marc Schieber, M.D., Ph.D., and Kevin Mazurek, Ph.D. with the University of Rochester Medical Center Department of Neurology and the Del Monte Institute for Neuroscience, which appears in the journal
Neuron, shows that very low levels of electrical stimulation delivered directly to an area of the brain responsible for motor function can instruct an appropriate response or action, essentially replacing the signals we would normally receive from the parts of the brain that
process what we hear, see, and feel.
«The successful retrieval of memories in AD mice
by increasing the number of spines for normal memory
processing only in the memory cells, rather than in a broad population of cells, highlights the importance of highly - targeted manipulation of
neurons and their circuits for future therapies.
According to the principle, the brain's cortex manages the tremendous amount of sensory information — images, sounds, smells, etc. — flooding it constantly
by reformatting the influx into various components called features, so that it takes very few
neurons to
process it.
Our goal is to use a new imaging system to monitor damage caused
by AD to the brain region that contains the insulated axons (analogous to cables) connecting the
neuron cell bodies (analogous to the central
processing unit of a computer).
Barcelona, studies the
process by which stem cells turn into
neurons, the type of brain cells that malfunction and die in HD.
«The successful retrieval of memories in AD mice
by increasing the number of spines for normal memory
processing only in the memory cells, rather than in a broad population of cells, highlights the importance of highly - targeted manipulation of
neurons and their circuits for future therapies,» said Tonegawa in a statement.
The innovative aspect of this activity was the notion that the concept of macroscopic devices could be extended to the molecular level, and that it was possible to design supramolecular systems that, upon stimulation with external energy stimuli such as UV / Visible light, are capable of performing a variety of specific functions: (i) systems for information
processing (e.g., wires, switches, antennas, plug / socket systems, extension cables, memories, logic gates, encoder / decoder, rudimentary
neuron - like systems), (ii) devices that when powered
by chemical energy or electrochemical energy or
by light exhibit machine - like behavior (e.g., piston / cylinder systems, shuttles, lifts, rotary rings, dendritic photo - switchable boxes), and (iii) components for artificial photosynthetic systems.
Surcharged
by the success of those efforts, the Jans next uncovered the principles and genes that control the
process by which the slender branches of
neurons, called dendrites, grow into densely interlacing forests.
10/10/2007 Researchers Reveal Repressor Protein Blocks Neural Stem Cell Development A protein known to repress gene transcription at the molecular level in a variety of
processes also blocks embryonic neural stem cells from differentiating into
neurons, according to a study
by University of California, San Diego and Howard Hughes Me... More...
We first sought to gain insight into the biological
processes that may be altered
by elevated miR - 181a expression in the mDA
neurons in PD [13].
In an effort to achieve these goals, we have established interdisciplinary partnerships devoted to the study of basic biological
processes and signaling pathways targeted
by neurodegeneration in Alzheimer's and Parkinson's disease, tauopathies, Down syndrome, neurometabolic disease (including obesity & diabetes), motor
neuron disease and traumatic brain injury.
The research team extrapolated the study to examine the
process by which the brain drives the activity of
neurons in bringing about concrete behavioral changes.