Sentences with phrase «processes of a human cell»

Autophagy is the garbage collection and recycling process of human cells.

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Organovo, a start - up in Los Angeles, is working on a process in which a bioprinter will squirt multiple layers of human tissue cells onto special paper.

If life can evolve from a single cell to complex humans, why couldn't a similar process effect life outside of this dimension?

Hammer and colleagues Dennis Discher and Frank Bates attempted to scale up this process to make vesicles more than 10 micrometers in diameter — the size of human cells.

Therefore, it is essential that we learn how specific types of chemical modifications normally regulate RNA function in our cells, in order to understand how dysregulation of this process contributes to human disease, says Cristian Bellodi.

The study results were found using mouse embryonic stem cells, which are good cell models for the study of processes seen in human stem cells.

Adding stem cells from human bone marrow to a broken diabetic bone enhances the repair process, increasing the strength of the newly formed bone, according to a laboratory - based study presented at the European Congress of Endocrinology in Dublin.

There are hundreds of RNA - binding proteins in the human genome that together regulate the processing, turnover and localization of the many thousands of RNA molecules expressed in cells.

The screening process identified three promising compounds, which were then tested for their ability to prevent Zika infection of human brain cells.

But Welte speculates that when internal temperatures do fluctuate in humans, as in the case of fevers, our cells may also need a way to coordinate the protein - building process.

Meanwhile, recent human studies indicate that aging is associated with an increase in somatic mutations in the hematopoietic system, which gives rise to blood cells; these mutations provide a competitive growth advantage to the mutant hematopoietic cells, allowing for their clonal expansion — a process that has been shown to be associated with a greater incidence of atherosclerosis, though specifically how remains unclear.

One clinical trial involves the drug CGF166, a one - time gene therapy, which, if proven successful in humans, could regenerate new hair cells within the cochlea that can signal the part of the brain that processes sound.

The researchers observed the effect of the synthetically produced molecule, JK - 31, on the growth and proliferation of a model human breast cancer cell line and found that it effectively blocked the protein cyclin - dependent kinase 1 (CDK1), which plays a key part in the process of the division of cancer cells, and therefore inhibited the proliferation of the cells.

The process, reported in Human Reproduction, utilizes DNA fingerprinting (an assessment of active genes in a given cell) to boost the success rate of IVF and lower the chances of risky multiple births by identifying which of several five - day - old embryos are most likely to result in pregnancy The new method, which will replace unproved alternatives such as choosing embryos based on their shape, is likely to up the success of women becoming pregnant and lower their chances of having multiple births.

The researchers reprogrammed the cells to create induced pluripotent stem cells in an FDA - compliant facility at the Broad Stem Cell Research Center; the use of this facility is an important step in the process as preclinical research moves toward human clinical trials.

The process enables some viruses to insert their genetic material into the DNA of healthy human cells, which can lead to tumors and other diseases.

Third, 40 to 60 percent of the cells grown using the process are either muscle cells or muscle progenitors, a high proportion compared to traditional non-genetic techniques of generating muscle cells from human ES and iPS cells.

The risk of developing severe malaria turns out to be strongly linked to the process by which the malaria parasite gains entry to the human red blood cell.

To see whether cancer stem cell renewal involves a chain of events similar to that used by embryonic stem cells, and whether the process was affected by oxygen levels, Semenza and graduate student Chuanzhao Zhang focused their studies on two human breast cancer cell lines that responded to low oxygen by ramping up production of the protein ALKBH5, which removes methyl groups from mRNAs.

Tests rely on either expensive equipment for computer - assisted analysis or, in hospitals that can not afford thousands of dollars» worth of machinery, a technician who analyzes sperm cells under a microscope, a process Shafiee says can be subject to human error.

«These two studies highlight the value of using an integrated multi-systems approach — including fruit flies, mice, and human cells — to discover mechanisms underlying disease processes.»

«Shutting off vital tumour growth processes can lead to the death of human brain tumour - initiating cells.

The laboratory process, described in the journal Scientific Reports, entails genetically modifying a line of human embryonic stem cells to become fluorescent upon their differentiation to retinal ganglion cells, and then using that cell line for development of new differentiation methods and characterization of the resulting cells.

An ear scaffold, left, provides the structure to grow human cells.A kidney stripped of cells, right, awaits an injection of human kidney cells, part of the process of engineering a new organ.

Programmed cell death, or apoptosis, is a natural process that kills billions of cells in a typical human body each day.

The new study shows that the synthetic compound is capable of inhibiting the activities of several DNA - processing enzymes, including the «integrase» used by the Human Immunodeficiency Virus (HIV) to insert its genome into that of its host cell.

Now, scientists at Boston University's Center for Regenerative Medicine (CReM) have announced two major findings that further our understanding of this process: the ability to grow and purify the earliest lung progenitors that emerge from human stem cells, and the ability to differentiate these cells into tiny «bronchospheres» that model cystic fibrosis.

In both humans and birds, cells process this gene in a way that produces both a full - length protein and a shorter version of the protein.

Autophagy is the «self - eating» process of consuming the portion of intracellular proteins in the cells of eukaryotes such as yeast, humans and plants.

Autophagy is the «self - eating» process of consuming unwanted elements in the cells of eukaryotes such as yeast, humans and plants.

Researchers found 53 existing drugs that may keep the Ebola virus from entering human cells, a key step in the process of infection, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai and the National Institutes of Health (NIH), and published today in the Nature Press journal Emerging Microbes and Infections.

At the July meeting of the European Society for Human Reproduction and Embryology in Madrid, scientists were horrified — and transfixed — by two presentations: one that explored adding cells to developing embryos and another that outlined a process of growing egg cells from aborted human fetHuman Reproduction and Embryology in Madrid, scientists were horrified — and transfixed — by two presentations: one that explored adding cells to developing embryos and another that outlined a process of growing egg cells from aborted human fethuman fetuses.

The researchers now plan further studies using XR - seq in bacterial cells, as well as in human and other mammalian cells where the process of excision repair is less understood.

A UCSF - led team has developed a technique to build tiny models of human tissues, called organoids, more precisely than ever before using a process that turns human cells into a biological equivalent of LEGO bricks.

The budding yeast, Saccharomyces cerevisiae, is a prime organism for studying fundamental cellular processes, with the functions of many proteins important in the cell cycle and signaling networks found in human biology having first been discovered in yeast.

The dome's structure inspired an explanation of the architecture of human red blood cells, the discovery of fullerene molecules (which take the form of buckyballs and carbon nanotubes), and ways to process data for robotic vision.

The researchers focused on one common epigenetic process known as methylation, in which methyl (CH3) groups attach in various patterns to the genes of human cells.

The results show, for the first time, that the process of swapping genetic information, known as recombination, happens not when the malaria parasite is inside the mosquito, as previously thought, but during the asexual stage of the parasite's lifecycle inside human blood cells.

These are some of the fastest migrating cells in the human body, and they are the first responders at damaged locations or areas of infection and begin the process of healing.

«If further studies validate that these processes are critical in human breast cancers,» Koshy notes, «the possibility exists that agents that favorably modify the biophysical properties of the extracellular matrix, or that target the receptors and signaling molecules associated with how cells sense this matrix, could be used as a new avenue for the prevention or treatment of breast cancers.»

In some human cell types, this process is controlled by a family of regulatory proteins called ESRP.

«While ciclopirox and deferiprone were developed for unrelated uses, Hartmut's knowledge of enzymes and pharmacology suggested that both drugs could influence some of the most basic processes that occur within human cells,» he says.

Although this human Gut Chip recreated the villus epithelium of normal intestine and enabled new insights into how flow and cyclic peristalsis affects intestinal differentiation and function, it could not be used to study processes that relied on normal intestinal cells from individual donors, which, for example, is crucial for studying patient - specific responses for personalized medicine.

New research from scientists at Huntsman Cancer Institute (HCI) at the University of Utah and collaborators at University of Utah Health (U of U Health) sheds light on the complex process that occurs in the development of human sperm stem cells.

In the Nature papers, the researchers compared gene transcription, chromatin modification and other processes that control gene activity in a wide range of mouse and human tissues and cell types.

But researchers believe that G4 structures can inhibit certain processes in the cells, including DNA replication, and have tied them to the development of cancer and neurodegenerative diseases in humans.

In human trials, researchers remove some of patients» T cells through a process similar to dialysis and then engineer them in a laboratory to add the gene for the CAR so that the new receptor is expressed in the T cells.

Over the years, scientists have seen more instances of such curious behavior during DNA repair — one of life's most fundamental processes — but whether it also happened in human cells was debated.

The discovery of cells» ultra-sensitivity for mechanical property of their environment is crucial to understanding basic physiological processes that underlie embryo development, tumor metastasis, wound healing and many other aspects of human health and disease.

Knowing how cells exert force and sense mechanical feedback in their microenvironment is crucial to understanding how they activate a wide range of cellular functions, such as cell reproduction, differentiation and adhesion — basic physiological processes that underlie embryo development, tumor metastasis, wound healing and many other aspects of human health and disease.