More sophisticated use of GM plants and animals to
produce human medicines — dubbed «pharming» — is a new field which promises to deliver drugs too complex to be synthesised in the test tube.
Not exact matches
NSF International's Raised Without Antibiotics certification provides consumers with assurance that the animal products they buy have been
produced without exposure to antibiotics used in
human medicine.
Proving that unfertilized eggs will
produce stable tissues in
humans remains an obstacle, says Alan Trounson, president of the California Institute for Regenerative
Medicine.
Using a mouse model of HSV - 1 as well as autopsied samples of
human adult and fetal tissues, investigators from Dartmouth College's Geisel School of
Medicine found that antibodies against HSV - 1
produced by adult women or female mice could travel to the nervous systems of their yet unborn babies, preventing the development and spread of infection during birth.
«This is a great study — it was very carefully done, it addressed an important organism in the
human microbiome, and it
produced some very interesting results,» says Martin Blaser, a physician and microbiologist at the New York University School of
Medicine in New York City.
In a screen of more than 100,000 potential drugs, only one, harmine, drove
human insulin -
producing beta cells to multiply, according to a study led by researchers at the Icahn School of
Medicine at Mount Sinai, funded by JDRF and the National Institutes of Health, and published online in Nature
Medicine.
Many scientists argue that so - called research cloning, in which cloned
human embryos might be used to
produce embryonic stem (ES) cells, could be a boon to
medicine.
For the animal experiments, Savio Woo of the Center for Gene Therapy at Baylor College of
Medicine in Houston and his colleagues first isolated liver cells from transgenic mice that
produce the
human protein a1 - antitrypsin in their livers, from where it is secreted into the blood.
«In this study, we show for the first time that fructose can be
produced in the
human brain,» said first author Janice Hwang, M.D., assistant professor of
medicine.
«At doses roughly equivalent to half or a single joint, ∆ 9 - THC
produced psychosis - like effects and increased neural noise in
humans,» explained senior author Dr. Deepak Cyril D'Souza, a Professor of Psychiatry at Yale School of
Medicine.
Suddenly, the idea of herds of identical prize bulls, or sheep
producing medicines for
humans in their milk, seemed wholly plausible.
Human -
produced noise in the ocean is likely harming marine mammals in numerous unknown ways, according to a comprehensive new report from the National Academies of Sciences, Engineering, and
Medicine.
Their work, published in Science Translational
Medicine, provides proof of concept for
producing antibodies against a broad range of
human pathogens.
iBET's infrastructure comprises 16 laboratories fully equipped with state - of - the - art technology (70 m2 each), including a BSL2 laboratory for working with viruses; a GMP Analytical Services Unit certified by the INFARMED (the Portuguese
medicines authority, EMA Portuguese branch) and by DGAV (the Portuguese veterinary authority) for quality control and batch release of
human and veterinary pharmaceuticals, biopharmaceuticals as well as experimental new drugs; a GMP Mass - Spectroscopy Unit that provides state - of - the - art MS services to the scientific community and Industry; a 2600 m2 bio-pilot plant supporting production and purification of proteins ATMPs and vaccines from bench top to 300 L scale and privileged access to GeniBET Biopharmaceuticals, an iBET spin - off
producing ATMPs under cGMP certification for phase I / II / III clinical trials.
Coleen McNamara, MD, a Professor of Internal
Medicine at the University of Virginia, recently discovered a B cell subset that
produces natural antibodies to protect from diet - induced atherosclerosis in mice, and she hopes to gain insights into the equivalent mechanisms in
humans.
Scientists at Penn State College of
Medicine, working alongside an international team of researchers, have
produced the most complete encyclopedia of functional elements in the mouse genome to date and compared it to the
human genome.
Researchers at the University of North Carolina at Chapel Hill School of
Medicine have transformed cells from
human skin into cells that
produce insulin, the hormone used to treat diabetes.
But because stem cells can become any kind of tissue,
human - animal research in the field of «regenerative
medicine» raises greater ethical issues and adds, for some, a visceral unease about the organism that could be
produced.
As we
produce more
human - relevant data with our Organ - Chips, we look forward to making a positive impact on informing R&D decisions, reducing drug candidate attrition in
human clinical trials, and helping to deliver better and safer
medicines to patients.»
The most profound
medicine is
produced in the
human system for free!
Researchers from the Department of
Medicine at the University of Virginia found that fasting for just two days
produced a 5-fold increase in
human growth hormone (HGH).
In August 2003, the Journal of Veterinary
Medicine carried an Italian study which showed that dogs also develop vaccine - induced cancers at their injection sites.5 We already know that vaccine - site cancer is a possible sequel to
human vaccines, too, since the Salk polio vaccine was said to carry a monkey retrovirus (from cultivating the vaccine on monkey organs) that
produces inheritable cancer.
A team of researchers led by Purdue Veterinary
Medicine Assistant Professor of
Human - Animal Interaction Maggie O'Haire has
produced valuable scientific data documenting the nature of the effect of service dogs on veterans suffering from post-traumatic stress disorder (PTSD).