Here about 750 cells
produce orexin (also known as hypocretin), a hormone that promotes wakefulness.
Not exact matches
Interestingly, those who suffer from narcolepsy, a disease in which people are excessively tired and may spontaneously fall asleep during the day, also lack
orexin due to a breakdown in the brain cells that
produce it.
Using mice, this study found that in obesity, CB1 cannabinoid receptors become enriched on the nerve terminals that normally inhibit
orexin neuron activity, and the
orexin neurons
produce more of the endocannabinoids to activate these receptors.