Sentences with phrase «produce other cell types»

Efforts to produce other cell types, such as liver cells, have proved far more difficult, he says.

The genes O, S, and K were known to help the cells become pluripotent, which allows them to produce any other cell type in the body.

Not exact matches

Scientists have identified as many as 80 others, which range from type 1 diabetes, which develops when the body attacks its insulin - producing cells, to multiple sclerosis, psoriasis, and rheumatoid arthritis.

The researchers dialed the skin cells back, developmentally speaking, to produce induced pluripotent stem cells (iPSCs)-- a special type of cell that can both self - renew, making more iPSCs, and differentiate, specializing into almost any other cell type.

Because these other skin cell types showed no signs of expansion or transformation, our analysis highlights pigment - producing cells as the originators of melanoma.»

The researchers have shown that it is possible to produce chromosome modifications in human cells that are genetically identical to those observed in leukemia and other types of human cancer.

Hookworm infections seem to provoke a mix of two different immune cells: type 1 T cells, which instruct other cells to directly attack pathogens, and type 2 T cells, which tell cells to produce antibodies.

COUNTLESS research projects around the world into cancer and other major diseases are producing bogus or misleading results because investigators are studying the wrong type of cell.

Unlike transplanted beta cells — or other types of real cells genetically engineered to release insulin for diabetes treatment (SN: 1/15/11, p. 9)-- these artificial cells could be mass - produced and have a much longer shelf life than live cells, says study coauthor Zhen Gu, a biomedical engineer at the University of North Carolina at Chapel Hill.

«There have been previous reports of other labs deriving beta cell types from stem cells, no other group has produced mature beta cells as suitable for use in patients,» he said.

In other words, there is a division of labor among various types of cells within the sponges, which produce the self - organized biological structures through a chain of simple reactions.

In principle, we hope to engineer T cells or other cell types to reside in the body long - term and produce therapeutics if they recognize disease or recurrence of disease.

A potential solution to this problem is to reprogram other cell types into functional beta - like cells, which can produce insulin but are distinct from beta cells and therefore are not recognized or attacked by the immune system.

It is believed to result from a combination of genetics and environmental factors such as irritants and allergens that drive T lymphocytes to produce factors that cause abnormal changes in keratinocytes, the predominant cell type in the outermost layer of skin, as well as changes in other cells in the underlying dermis.

The stem cells produced through this therapeutic cloning would, like other embryonic stem cells, be capable of developing into many cell types and serve as a repair system for whatever part of the body required replenishment at the time.

In others, the researchers altered a gene that regulates phospholipids, the primary type of fat in cell membranes, which spurred the cells into producing more cholesterol on their own.

But the extracted tissue began producing insulin, glucagon and other hormones after the newly identified cells were added, indicating that they were indeed progenitors capable of differentiating into all the islet cell types, including beta cells.

We're manipulating genes in the cell nucleus to produce specific proteins, changing the normal recipe for growth and maturation, and transforming adult cells into a new type of cell with the ability to morph into any other cell type,» said Cooke, senior author and chair of the Department of Cardiovascular Sciences.

The findings suggested that different types of blood cells produce vastly different amounts of protein per hour, and stem cells in particular synthesize much less protein than any other blood - forming cells.

In addition, the molecular beacons technique http://www.lependart.com could have broad applications across regenerative medicine, because it could be used with other types of cells produced from stem cell cultures, such as brain cells or insulin - producing islet cells.

ViaCyte is aiming to eliminate rigorous insulin treatment and glucose testing by engineering a type of stem cell that produces insulin and other hormones that regulate sugar levels.

«When one cell type produced Wnt1, which we know the tumor depends on, the other type sensed it.»

In separate experiments reported in Nature — one with mice, the other transplanting human stem cells into mouse bone marrow — researchers demonstrated techniques with the potential to produce all types of blood cells.

The study relates to a particular type of vaccine (killed) against a particular virus, influenza, though the findings might hold true for other killed vaccines and for those vaccines consisting only of proteins produced by GM in bacteria, yeast or insect cells, against diseases such as hepatitis B (HBV) and human papilloma virus (HPV, the causative agent of cervical cancer).

Other research has shown that oxygen - deprived cells in the retina produce a type of protein called vascular endothelial growth factor (VEGF), which triggers the growth of new blood vessels in the retina.

SLC16A11 belongs to a family of genes known to transport molecules across cell membranes, but the proteins that genes produce can perform many different roles in the body, and they can be active in some tissue types but not others.

This suggests that the behaviour of transcriptional networks downstream of Nanog, FGF signalling, and other key ES cell regulators produce an attractor or attractor states occupied by these cell types.

No other cells in the body produce this type of protein, therefore, if the test determines the presence of the protein, you are producing cancer cells.

In type 1 diabetes, on the other hand, more than 90 percent of the insulin - producing cells have been destroyed.

There are two main types of stem cell: one produces bone, cartilage, marrow fat and other connective tissues, to repair and maintain the skeletal system.