Sentences with phrase «produce oxidative»

Unbound iron can interact with vitamin C to produce oxidative stress.

The body protects itself against free radicals using antioxidants, but if the level of antioxidants is too low, radiation produces oxidative stress and genetic damage, which leads to aging and death.

Studies show that toxic metals contribute to brain diseases by producing oxidative stress and aluminum is one of the worst offenders.

Scientists are clear that toxic metals damage brain tissue and lead to degenerative disease by producing oxidative stress — and aluminum is one of the worst offenders.

Not exact matches

The potential health benefits of the sweet potato sporamins in helping prevent oxidative damage to our cells should not be surprising since sweet potatoes produce sporamins whenever subjected to physical damage to help promote healing.

These adrenal stimulants can produce dirty energy in the form of blood sugar swings and oxidative stress.

The researchers experimented with inducing oxidative stress in a human cell line culture with and without VCOP (virgin coconut oil polyphenols) to observe how VCOP positively promoted catalase, a very important enzyme in protecting the cell from oxidative damage, and glutathione (GSH), a self - recycling antioxidant produced by the liver.

Researchers focused on two pathways that produce energy in muscles, glycolysis (sugar metabolism) and mitochondrial oxidative phosphorylation (OXPHOS) in both young and middle - aged rats that were fed a normal diet or a calorie - restricted diet.

«The chemicals produced by cooking meats at high temperatures induce oxidative stress, inflammation and insulin resistance in animal studies, and these pathways may also lead to an elevated risk of developing high blood pressure,» said Gang Liu, Ph.D., lead author of the study and a postdoctoral research fellow in the department of nutrition at the Harvard T.H. Chan School of Public Health in Boston.

Mitochondria are found in cells and they use oxygen to produce energy in a process called oxidative metabolism.

«Tumor cells produce larger quantities of H2O2 and use oxidative signals at higher levels than normal cells in order to drive their own growth,» says Mirko Sobotta, first author of the publication.

Mitochondria produce energy for cells through oxidative metabolism, but the process produces toxic byproducts that can accumulate and cause defects in the cell's mitochondria.

The second method, called oxidative phosphorylation, produces free radicals, reactive forms of oxygen that can be particularly harmful to a cell's DNA.

Using spectral readings from telescopes at the Keck Observatory in Hawaii, Hand has found high levels of oxidative chemicals such as sulfate, oxygen, sulfur dioxide and hydrogen peroxide on Europa's surface, which are produced as ionizing radiation from Jupiter scours it, splitting apart water molecules and sulfur compounds in the uppermost layers of its ice.

«We have observed that it is only when silver nanoparticles enter inside the cells that they produce serious harm, and that their toxicity is basically due to the oxidative stress they create,» explained the chemist Guillermo Orts - Gil, project co-ordinator.

Mice deficient in critical innate immune functions such as Toll - like receptor signaling or oxidative burst production spontaneously produce high - titer serum antibodies against their commensal microbiota.

«Oxygen by - products produced during normal metabolism can cause oxidative damage to biomolecules in cells, such as DNA and RNA,» explains Jian - Ping Cai, a researcher involved in the study.

The oxidative signals produced by mitochondria are delicately balanced by the antioxidant defenses in healthy cells.

Although reactive oxygen species can damage cells when produced in high amounts, according to a study published online Sept. 5, 2017 by Science Signaling and featured on the journal's cover, these oxidative species are crucial signals that start the process of repairing myofiber.

«What we've done is figure out that mitochondria need to produce a very specific oxidative signal in response to muscle damage in order to help injured muscles repair.»

«Since mitochondria are the energy powerhouses of the cell, they're also the place where the most free radicals (which play a role in oxidative stress) are produced.

Although ethylene (or ethene) is best known as a plant hormone, humans also produce it as consequence of oxidative stress, caused for example by the UV radiation from the sun.

Fat cells produce excessive reactive oxygen species, which can damage cells in a process called oxidative stress.

That phenomenon, known as oxidative stress, occurs when the cells of older adults begin to produce too much superoxide and other reactive oxygen species.

The imbalance created by oxidative stress produces peroxides and free radicals, which contribute to a number of degenerative conditions, including aging.

Also called OXPHOS Complexes (Oxidative Phosphorylation) that make redox NADPH be used as electron donor through ETC and allow mitochondria to produce cell energy ATP.

The Keap1 - Nrf2 system has evolved to respond to intracellular oxidative stress; in particular the generation of reactive electrophiles produced from oxidation of endogenous cellular constituents as well as xenobiotics [2]--[4].

Oxidative stress is generated by reactive oxygen species (ROS) produced in response to metabolic activity and environmental factors.

This DNA becomes damaged in the course of normal cellular processes, and certain forms of mitochondrial DNA damage - to the thirteen genes needed for oxidative phosphorylation - produce malfunctioning mitochondria that can overtake their cells, either by replicating more readily or being more resistant to quality control mechanisms.

Over time however, mutations in these genes occur as a result of constant exposure to reactive oxygen species produced by oxidative phosphorylation, the mitochondrial energy generation process.

HZE ions, for example, produce greater adverse effects on cellular physiology through increased genetic alterations and perturbations to redox metabolism, leading to persistent elevations in oxidative stress13, 14,15.

When free radicals are high in a normal way would that produce a high oxidative stress test (the urine test that reacts in the presence of malondialdehyde)?

Over time the amount of DNA / RNA diminish and become damaged due to increased oxidative stress and will consequently produce flawed copies of our own genetic blueprint.

It has been shown that consuming onion produces changes in the metabolism of fatty acids, aiding recovery from oxidative damage due to excess of cholesterol.

The reduction in oxidative stress has been attributed to papaya's lycopene content and ability to remove excess iron, which is known to produce free radicals (12, 13).

The body uses molecular oxygen to produce energy via oxidative phosphorylation in the mitochondria.

Do you think that that would be enough oxidative stress to produce some of these things that we're seeing, extremely high cortisol, low thyroid, low luteinizing hormone, high levels of superoxide dismutase, and low levels of glutathione?

When they are produced, oxidative stress occurs through the mentioned targets.

Oxidative stress can overwhelm the mitochondria of all cells (including the liver), making it difficult for them to function — since the mitochondria produce energy for the cells.

if stearic acid in cacao is healthy why would stearic acid in lard harm us, plants and animals produce the most saturated fat that will melt at their body temperatures, to reduce oxidative stress.

The results showed that zinc and chromium can reduce oxidative stress to the same degree but the combination of both minerals produced better results.

Aging - associated increases in oxidative damage to key enzymes results in their structural deformation and decreased binding affinity for the co-enzyme, causing a decrease in enzyme funtion.8 Ames» research has demonstrated that increasing the availability of acetyl L - carnitine and α - lipoic acid, two nutrients that serve as mitochondrial enzyme co-factors, restores the velocity of the reactions (KM) in the related enzymes, and thus restores aging mitochondria's ability to produce youthful levels of ATP.9 10 11 12 13 Part II focused on the inter-relationships among the folate, methylation and transsulfuration pathways, whose dysfunction results in increased free radical production coupled with disruption of glutathione (GSH) synthesis, thus accelerating mitochondrial decay and aging.

Ketones produce far less oxidative stress when turned into energy when compared to glucose.

CoQ10 administration has been shown to reduce production of ROS by mitochondria exposed to Aβ in animal models of diabetes.18 With the AD brain struggling to produce energy and under great oxidative stress, CoQ10 could be a powerful adjunct.

Third, the brain could be redirecting its metabolic machinery toward utilization of fuels other than glucose, such as fatty acids and ketone bodies, which produce less oxidative stress and are, in fact, more efficient fuels.14, 46,47

They produce free - radicals which then go on to induce oxidative stress in cells and tissues throughout the body, and they strain and degrade the function of the liver, one of the body's most important detoxifying mechanisms.1

In instances of higher turnover of cells seen with excess oxidative damage due to iodine excess and selenium deficiency, more antibodies are produced, and an immune system shift can be induced, resulting in the failure to recognize self from non-self.

Lipoic acid protects the mitochondria, the energy producing factories of cells, from oxidative stress and toxicity like nothing else (9).

While our bodies are adept at producing antioxidants that balance the effects of oxidative stress, that ability lessens as we age and our skin — already compromised by the above assaults — produces less of the antioxidant - rich oils that protect it.

A free radical is a molecule produced in the body that lacks an electron which scavenges the body, taking electrons from structures which wouldn't otherwise give them away and causing oxidative stress.