Sentences with phrase «produce short sequence»

Current massively parallel DNA sequencing technologies produce short sequence reads that are often unable to resolve haplotype information.

Not exact matches

By this directed evolution we were able to produce ribozymes that can catalyze the copying of relatively short strands of other RNAs, although they fall far short of being able to copy polymers with their own sequences into progeny RNAs.

Bar coding typically involves sequencing a few short segments of animal DNA from the mitochondria, the mini-organs that produce energy within every cell.

MicroRNAs are short RNA molecules that typically bind to complementary sequences in messenger RNAs, thereby controlling the amounts of specific proteins produced by cells.

Conventional genetic screening looks for specific mutated sequences of DNA, but the Dutch test simply searches for proteins which are shorter than those produced by healthy genes.

One sequencing technology used by the researchers produces massive amounts of very short reads — about 150 to 250 bases in length.

The Y chromosome, like all DNA, is composed of a series of molecules called «bases» that are represented by the letters A, T, C, and G. Current genetic sequencing technologies produce «reads» of sequence that are much shorter than the entire length of the chromosome.

To their surprise and dismay, the genome turned out to contain long stretches of noncoding and repetitive DNA, which made it difficult to piece together the short reads produced by the sequencing machine.

The differences between coding versus noncoding trees were not solely due to shorter sequence length of the coding data, because the full coding data set (13.3 million bp for c123) produced a tree with fully supported (100 % BS) relationships that were incongruent with those fully supported in the intron (19.3 million bp), TENT (37.4 million bp without the third codon position), and WGT (322.1 million bp)(Figs. 2 and 5B, and table S3).

These differences are not merely due to shorter alignments of the exon and UCE sequences, because each accounted for ~ 25 % of the TENT data, similar in sequence length to the random 25 % subset of the TENT with introns (table S3) that produced a tree with a higher average BS and a topology closer to the full TENT (Fig. 5A and fig.

Using the 58 eggs confiscated in the Folgosa case back in 2003, she and her team searched for short DNA sequences that coded for a piece of the ribosome, the cell's protein - producing factory.

Massively parallel sequencing technologies, while increasing the speed, improving the accuracy, and reducing the cost of genome sequencing, typically produce only short stretches of sequences called «reads» After sequencing, the reads are pieced back together with genome assembly software.

But in the freezing and thawing soil layer, sequencing showed that bacteria within the soil samples were producing some intriguing proteins, including enzymes that snip long chains of carbon molecules, like cellulose from plants, into shorter, simpler sugar compounds that the bacteria can use as fuel.

Yet those who produce next - gen sequencing data are rapidly adopting this universal short read data format as the de facto standard.

Modern DNA sequencing technologies predominantly produce short read sequences.

The instrument now available from Solexa Ltd, produces millions of short DNA sequences of 25 nt each.

There isn't much to say about it intellectually, but for a group of filmmakers who grew up making short films and finding themselves producing special effects and stop - motion animated sequences for films like Pee - Wee's Big Adventure, Killer Klowns from Outer Space is an admirable effort.

In addition to the installation of paintings and excerpted text, two publications were produced as supplements to the exhibition: one was a series of six large - scale, hand - bound books — each named after a character from the short story — consisting of five original watercolors by Innes, and the short story in its entirety; the second publication is a book which also includes Tóibín's story alongside reproductions of all 101 watercolors featured in the exhibition and an introduction written by Sean Kelly which details the sequence of events leading up to the proposed collaboration.

Through special preparation of DNA long fragment information can be retrieved even by sequencing short strands of DNA — by combining the short and long read information the original DNA sequence is pieced together — producing the reference assembly.