Sentences with phrase «produced by their gene»

Killary and colleagues earlier identified a cluster of genes involved in cancer migration and then analyzed the proteins produced by those genes.

The technique involves designing double - stranded RNA molecules that match a sequence in the RNA produced by the gene you want to inactivate.

In 2010 biologist Valerie Hu of the George Washington University Medical Center and her colleagues found that brains of people with autism have low levels of a protein produced by a gene called retinoic acid — related orphan receptor - alpha (RORA).

The protein produced by this gene protects the chromosome ends of the DNA from damage, and controls telomere maintenance by the telomerase enzyme.

The analysis suggested that a protein produced by a gene called Olig2, which is only expressed in the neural progenitors that create motor neurons, promotes motor neuron formation by interfering with the activity of several members of another gene family — the Hes genes.

Now, Harry Moore and Bikem Soygur at the University of Sheffield, UK, have shown that a protein called syncytin - 1, produced by a gene that humans gained from viruses 25 million years ago, probably plays a vital role in this process.

The mouse atlas was produced using a method called «in situ hybridisation», in which thin slices of brain tissue are bathed in a solution containing molecular probes that bind to messenger RNA sequences produced by each gene.

Drugs like trastuzumab and lapatinib block the protein produced by the gene.

When researchers want to study a specific gene, they often make slight modifications so a special protein tag that produces fluorescent light can attach to the proteins produced by their gene of interest.

Messenger molecules — messenger RNAs — are produced by these genes at a certain time of day.

The team found lower levels of TRNP1 in areas that were destined to form folds, and higher levels in areas that would not have developed them, suggesting that the protein produced by the gene inhibits more complex brain development in humans as well as in mice.

«Naturally occurring «GM» butterflies produced by gene transfer of wasp - associated viruses.»

There is a caveat, however: The enzyme Hunter patients now receive does not cross the blood - brain barrier, the tight network of cells that protects the brain from pathogens, and the livermade enzyme produced by the gene edit may not either.

Messenger molecules - messenger RNAs - are produced by these genes at a certain time of day.

Dr. Iavarone and his colleagues suspected that glioblastomas might be addicted to proteins produced by gene fusions.

Therefore, investigators are searching for drugs that can increase the amount of normal protein produced by this gene.

Our research combines diverse techniques ranging from genomics, computational biology, tumour imaging, in vitro and in vivo functional models to study biological and clinical phenotypes.The proteins produced by these genes may serve as targets for novel chemotherapy drugs and other cancer treatments, or imaging scans.

Researchers have isolated the gene involved, SMN, as well as the protein produced by the gene.

The most frequent high penetrance melanoma gene found to be mutated in melanoma families is CDKN2A and the protein produced by the gene is called p16.

From the same group studied above, Dr. Ornish measured the activity of an enzyme produced by genes, telomerase, believed to be involved in slowing the aging process.

Not exact matches

Ho - mo - logous or - gans are now known to be produced by totally different gene complexes in the different species.

While the entity generated by deleting or disabling early embryonic genes would produce only an unorganized collection of stem cells, it would do so after a period of what appears to be relatively normal development.

As differentiation continues, various genes are «switched off» but stem cells, even in adults, retain a certain pluripotency in order to produce fully differentiated cells lost by damage or ageing.

Instead, scientists used genetic modification techniques to develop Golden Rice by using genes from maize and a common soil microorganism that together produce beta - carotene in the rice grain.

Scientists have pinpointed a gene that enables rice plants to produce around 20 % more grain by increasing uptake of phosphorus.

The decision contradicts earlier recommendations by organizers of a global summit on human gene editing, who concluded that gene editing with molecular scissors such as CRISPR / Cas9 should not be used to produce babies (SN: 12/26/15, p. 12).

Fiers found that by linking M2e genes to HBc genes, the bacteria would produce viruslike particles studded with M2e.

The SRY (sex - determining region Y) gene on the male's Y chromosome orchestrates the formation of the testes, while the gonadal precursor will differentiate into an ovary by default (in the absence of the steroids produced by the testes).

The study, which is published in the journal Molecular Psychiatry, describes a possible mechanism for how the gene variant produces clinical symptoms by affecting levels of specific proteins in the brain.

In a 2016 study, Yang, Gomez - Pinilla and colleagues reported that hundreds of genes can be damaged by fructose and that an omega - 3 fatty acid called docosahexaenoic acid, or DHA, seems to reverse the harmful changes produced by fructose.

A team led by Byeong - Chun Lee of Seoul National University in South Korea created the dogs by cloning fibroblast cells that express a red fluorescent gene produced by sea anemones.

Turlings's team is now looking into creating super-resistant maize by inserting the gene for caryophyllene into plants that are already engineered to produce the Bt toxin against rootworms.

ORDINARY cells from people with a genetic disease can be «fixed» by gene therapy and then reprogrammed to be stem cells that will produce a limitless supply of defect - free cells.

However, last August a team headed by plant ecologist Allison Snow at Ohio State University demonstrated that this same gene might produce some very tough weeds: She found that wild sunflowers crossed with Bt sunflowers produced offspring that suffered significantly less insect - related damage and produced 50 percent more seeds than control plants without the gene.

By binding onto these genes, Bcl6 deactivates the DNA, stopping genes from producing RNA and proteins.

Human cells infected by the viruses produced the gene products, giving T cells an advance exposure to them.

Using a genome - wide genetic screen, Dr. Gelman and colleagues identified a previously unknown metastasis suppressor — the FOXO4 protein, which belongs to a family of genes that are produced by all human cells.

One team, led by scientists in the United Kingdom and Brazil, drove more than 1,200 miles across Brazil — «a Top Gear — style road trip,» one scientist quipped — with a portable device that could produce a complete catalog of the virus's genes in less than a day.

The virus is produced by a reassortment, in which human - adapted H1N1 swaps genes with an H2N2 bird flu.

Humans are still evolving and producing new gene variants, and one of them may give protection against becoming addicted to alcohol - by stopping us drinking altogether

Sure enough, plant root cells that harbor fungal arbuscules increase their expression of genes involved in producing such lipids by 3000-fold.

By microinjecting a specially engineered gene into the mosquitoes» eggs, the scientists produced insects that were unable to transmit the disease when they reached adulthood.

One way to get many types of cells or proteins from the same genetic starting material is by mixing and matching different parts of one gene to produce multiple gene readouts, a phenomenon known as alternative splicing.

By tweaking different fly genes and counting how many neuron types were produced as the flies matured, the team identified a network of five genes that work together like coordinated control switches to guide the precursor cells» transformation to mature neurons.

It has multiple hosts and can evolve by mutation but also reassortment (when two closely related strains infect the same host and exchange gene segments, producing new strains — a process distinct from mutation, when the RNA of a virus is miscoded during replication).

They bond to proteins called PIWI and guide them to the messenger RNA produced by the jumping genes, which the PIWI protein then destroys.

Using high - throughput DNA sequencing, the researchers located mutations in bacterial genes that resisted the toxicity of growth inhibitors produced by bacterial viruses.

By studying infected cells grown in a laboratory, the team found that a large number of CMV's genes help it hide from the immune system by allowing it to destroy many of the proteins produced by the body during virus infection and preventing them from activating immune cells to destroy the viruBy studying infected cells grown in a laboratory, the team found that a large number of CMV's genes help it hide from the immune system by allowing it to destroy many of the proteins produced by the body during virus infection and preventing them from activating immune cells to destroy the viruby allowing it to destroy many of the proteins produced by the body during virus infection and preventing them from activating immune cells to destroy the viruby the body during virus infection and preventing them from activating immune cells to destroy the virus.

This epimutation is produced by a mutation in an adjacent gene.

Also in contrast to the experiments in China, those led by Mitalipov reportedly produced very few «off - target» effects, or editing of genes that CRISPR was supposed to leave alone.