If bacteria
produces abnormal proteins and acids, there's a bad environment within the large intestine indicates an unhealthy environment.
The fused gene in turn
produces abnormal proteins that destabilize entire chromosomes, resulting in aggressive cancers.
If bacteria
produces abnormal proteins and acids, there's a bad environment within the large intestine indicates an unhealthy environment.
This produces an abnormal protein that disrupts cell growth control.
Other genetic defects associated with hypertrophic cardiomyopathy — six different genes have been linked to the disease — may work similarly by
producing abnormal proteins involved in contraction, says Sweeney.
These hybrid genes, formed from two previously separate genes,
produce abnormal proteins that can be a catalyst to faster and / or further cancer growth.
No genes that
produce abnormal proteins were found, but instead the elevated risk appears to come from groups of tightly - linked DNA sequences called «haplotypes» that regulate the expression of protein - coding genes.
Not exact matches
The team's key discovery was that stem cells lacking an enzyme responsible for pseudouridine modification of RNA, known as PUS7,
produce abnormal amounts of
protein.
In multiple myeloma, normal plasma cells transform into malignant myeloma cells and
produce large quantities of toxic
abnormal immunoglobulin called monoclonal
protein that can damage multiple organs.
Multiple myeloma is preceded by a blood disorder called monoclonal gammopathy of undetermined significance (MGUS) in which
abnormal plasma cells
produce many copies of an antibody
protein.
These can then trigger normal
proteins to also misfold,
producing a chain reaction that clogs the brain with
abnormal proteins and so causing diseases such as vCJD.
Of particular interest are the emerging techniques for genomics and proteomics, which allow profiles of gene expression and
protein synthesis to be
produced and comparisons to be made between normal and
abnormal cells, as well as between cells before and after exposure to medicines or toxic chemicals.
What these illnesses have in common is that they're caused by
abnormal proteins that accumulate in or between brain cells to form plaques,
producing damage that causes mental decline and early death.
This particular liver cancer arises from a mutation that
produces an
abnormal form of the enzyme that is the topic of this current work,
protein kinase A, and alters the enzyme's role in cell signaling.
Using a multi-disciplinary approach involving electrophysiological, cellular and biophysical techniques, the researchers found that parts of the prion
protein lacking the «brake» region
produced abnormal electrical currents in cells.
The researchers also discovered that c9RAN
proteins produced by the
abnormal RNA can be measured in the spinal fluid of ALS patients.
The researchers found that the ALS / FTD mutation
produces an
abnormal version of a
protein called TIA1 that is a building block of such organelles.
Rather, the mutation
produces an
abnormal version of a
protein involved in a process called phase separation in cells.
In cancer cells, the drugs
produce a substantial increase in the display of
abnormal proteins on the cells» surface.
What these illnesses have in common is that they're caused by
abnormal proteins that accummulate in or between brain cells to form plaques,
producing damage that causes mental decline and early death.
R6 / 2 mice have been genetically altered with an
abnormal gene that makes them
produce a harmful fragment of the mutant huntingtin
protein
Sometimes, however — particularly as we age, and when we consume too many sugary or high - glycemic foods — these sugars react with
proteins and fats in an
abnormal way,
producing harmful molecules called «advanced glycation endproducts (conveniently acronymned: AGEs).»