UCLA researchers have discovered a subset of people with hypertriglyceridemia whose bodies
produce autoantibodies — immune - response molecules that attack their own proteins — causing high levels of triglycerides in the blood.
The patients without diabetes
produced autoantibodies that completely impaired the activity of a subtype of interferon known as interferon - alpha, which is produced by the immune cells and may cause inflammation.
The auto - reactive B cells
produced autoantibodies that mistakenly targeted proteins within their own body, in particular targeting immune inflammatory molecules called interferons and interleukins.
This could potentially trigger the immune system to
produce autoantibodies.
But what factors drive the development of groups of B cells, called autoreactive B cells,
that produce autoantibodies in lupus?
In light of this new information, it appears for children who
produce autoantibodies to the folate receptor alpha, camel milk would be contraindicated and should be avoided.
Not exact matches
However, a new study of children from Sweden and Finland shows that the vaccine increased neither the risk of developing
autoantibodies against insulin -
producing beta cells nor the occurrence of type 1 diabetes.
* In type 1 diabetes, the insulin -
producing cells in the Langerhans islets of the pancreas are destroyed because they are attacked by the body's immune system (formation of islet
autoantibodies against structures of the beta cells).
In these diseases, the body
produces anti-thryoglobulin
autoantibodies that cause the immune system to attack the patient.
By age 8 1/2, 46 of the children had
autoantibodies to their own insulin -
producing beta cells; as weight and BMI went up, so did their risk.
At the same time, 30 percent of those with type 2 diabetes had the same
autoantibodies to their beta cells — the insulin -
producing cells in the pancreas — associated with type 1.
Instead of
producing antibodies to fight an infection, these groups pump out specialized
autoantibodies that efficiently attack healthy tissue.
This is called autoimmunity, in which the immune system fails to recognize its own cells and
produces antibodies against its own tissues, also known as
autoantibodies.
«In patients with lupus, we found that their natural defense system just continued to
produce more and more abnormal responses —
autoantibodies — up until the time they were diagnosed with the disease,» said Judith James, M.D., Ph.D., of OMRF and OUHSC, one of the study's co-authors.