Sentences with phrase «produces synergistic»

In addition, combining the anti-RANKL antibody with ipilimumab produced a synergistic effect and helped prolong survival.

An overlooked loop structure of the folate biosynthetic pathway is crucial to produce synergistic activity of these two antibiotics,» said Minato.

It combines the highest grade of low dust extruded palletized activated carbon with premium ion exchange resins to produce a synergistic formula for the health and well - being of aquarium inhabitants.

Combining alcohol with another drug and they are likely to produce a synergistic effect which no one can predict.

Not exact matches

«There are synergistic products like fresh produce, but they have different cheeses, sauces and pepperonis, for example.

A combination of the compound and an antibiotic produced «a synergistic effect,» she says, that worked better than either approach alone.

This is in accordance with previous reports that decitabine and 5 - azacytidine produce a marked synergistic effect in combination with suberoylanilide hydroxamic acid and romidepsin in T - lymphoma cell lines by modulating cell cycle arrest and apoptosis.26, 27 As a mechanism of action, KMT2D mutations of B - lymphoma cells promote malignant outgrowth by perturbing methylation of H3K4 that affect the JAK - STAT, Toll - like receptor, or B - cell receptor pathway.28, 29 Here our study indicated that dual treatment with chidamide and decitabine enhanced the interaction of KMT2D with the transcription factor PU.1, thereby inactivating the H3K4me - associated signaling pathway MAPK, which is constitutively activated in T - cell lymphoma.13, 30,31 The transcription factor PU.1 is involved in the development of all hematopoietic lineages32 and regulates lymphoid cell growth and transformation.33 Aberrant PU.1 expression promotes acute myeloid leukemia and is related to the pathogenesis of multiple myeloma via the MAPK pathway.34, 35 On the other hand, PU.1 is also shown to interact with chromatin remodeler and DNA methyltransferease to control hematopoiesis and suppress leukemia.36 Our data thus suggested that the combined action of chidamide and decitabine may interfere with the differentiation and / or viability of PTCL - NOS through a PU.1 - dependent gene expression program.

However its usefulness is that it tends to produce a good synergistic effect when mixed with other sweeteners.

Our formula is a synergistic blend of innate (produced in the body) micronutrients, anti-inflammatory compounds, botanicals and herbs that deliver greater positive coefficient results.

I know plant - based foods can be filling due to their fiber, but this natural pairing creates a wonderful synergistic health effect in order to rid your body of toxins that were produced during the workout while at the same time building your muscle better than it was before.

Biokleen of Vancouver, Washington, offers its line of Bac - Out products, which, according to its website, «offer a unique and synergistic blend of live enzyme - producing cultures that naturally break down stains and odors.»