Sentences with phrase «producing abnormal cells»
Healthy RPE cells can be stressed to produce abnormal cells that display features of AMD.
http://www.closerlookatstemcells.org/ Not exact matches
The team's key discovery was that stem cells lacking an enzyme responsible for pseudouridine modification of RNA, known as PUS7, produce abnormal amounts of protein.
To do so they focused on keratinocytes, a specific type of skin cells with a key role in psoriasis because of their abnormal growth and ability to produce large amounts of inflammation promoting factors.
Healthy plasma cells produce antibodies that fight infection in the body, but myeloma cells produce high levels of abnormal antibodies that, when the cancer cells accumulate, they crowd out production of other important blood cells, both red and white.
In multiple myeloma, normal plasma cells transform into malignant myeloma cells and produce large quantities of toxic abnormal immunoglobulin called monoclonal protein that can damage multiple organs.
Multiple myeloma is preceded by a blood disorder called monoclonal gammopathy of undetermined significance (MGUS) in which abnormal plasma cells produce many copies of an antibody protein.
This caused atypical growth of blood - forming stem cells that were more likely to produce the abnormal B cells most common in B - ALL.
Of particular interest are the emerging techniques for genomics and proteomics, which allow profiles of gene expression and protein synthesis to be produced and comparisons to be made between normal and abnormal cells, as well as between cells before and after exposure to medicines or toxic chemicals.
The new study revealed that pancreatic cancer cells not only send signals that make macrophages produce abnormal amounts of dectin - 1 surface receptors, but also that make tumor cells themselves express high levels of galectin - 9.
In sickle cell disease, individuals have two copies of a genetic mutation that produces an abnormal change in hemoglobin, the primary molecule that carries oxygen in the blood.
What these illnesses have in common is that they're caused by abnormal proteins that accumulate in or between brain cells to form plaques, producing damage that causes mental decline and early death.
This particular liver cancer arises from a mutation that produces an abnormal form of the enzyme that is the topic of this current work, protein kinase A, and alters the enzyme's role in cell signaling.
This produces an abnormal protein that disrupts cell growth control.
Using a multi-disciplinary approach involving electrophysiological, cellular and biophysical techniques, the researchers found that parts of the prion protein lacking the «brake» region produced abnormal electrical currents in cells.
It is believed to result from a combination of genetics and environmental factors such as irritants and allergens that drive T lymphocytes to produce factors that cause abnormal changes in keratinocytes, the predominant cell type in the outermost layer of skin, as well as changes in other cells in the underlying dermis.
Instead of producing healthy lymphocytes, white blood cells that fight infections, his bone marrow was unleashing abnormal lymphocytes into his bloodstream.
Rather, the mutation produces an abnormal version of a protein involved in a process called phase separation in cells.
In cancer cells, the drugs produce a substantial increase in the display of abnormal proteins on the cells» surface.
What these illnesses have in common is that they're caused by abnormal proteins that accummulate in or between brain cells to form plaques, producing damage that causes mental decline and early death.
In diseases like leukemia, a kind of cancer, the bone marrow produces abnormal blood cells.
The elevated incidence of glomerulonephritis in p21 - deficient mice, with increased severity among females, has been reported previously (35) and is attributable to an autoimmune process produced by abnormal proliferation of memory T - cell lymphocytes.
Each MPN is a different condition, but they are thought to be caused by an abnormal cancer stem cell that may have acquired genetic mutations that make it unable to produce blood cells normally
These cells produce factors (e.g. sKITL and MMP9) that normally keep the stem cells from differentiating into abnormal myeloid cells.
And according to recent studies conducted in Japan, the full ripe bananas with dark patches on their skin produce the largest quantity of TNF (Tumor Necrosis Factor), a cytokine that fights abnormal tumor cells in the body by stimulating the production of white blood cells and assisting their communication.
Sunflower seeds are also a good source of selenium, which has been shown to induce DNA repair and synthesis in damaged cells, to inhibit the proliferation of cancer cells, and to induce their apoptosis, the self - destruction mechanism the body naturally produces to eliminate worn out or abnormal cells.
Abnormal adrenal rhythms can alter the cells» ability to produce energy.
Essentially, the aim is to genetically alter patients» own blood stem cells so they don't produce abnormal hemoglobin.
When white blood cells multiply in an abnormal and uncontrolled way, these immature cells take over, literally crowding the bone marrow thereby preventing it from producing healthy blood cells and causing a shortage of red blood cells.
This means that abnormal blood cells can be produced or that production of normal cells can be halted due to an action of chloramphenicol on patient bone marrow.