Sentences with phrase «producing affected dogs»

The purpose of identifying carriers is to ensure that a carrier is not bred to another carrier, thus producing affected dogs.
In a short time we can prevent producing Affected dogs and reduce the number of Carriers to eventually eliminate this disease just as we are working towards doing with PRCD and FN.
By judiciously using the DNA test information, breeders can minimize the risk of producing affected dogs while maintaining the genetic diversity of the breed.
While this may all seem very complicated, the good news is that tests are available that can help breeders decrease the risk of producing affected dogs.
Knowing which dogs carry epilepsy genes enable breeders to avoid producing affected dogs.
Even so, breeders should take steps to avoid producing affected dogs.
However, for breeders with dogs at high risk of being carriers and no genetic test, it is the only tool that objectively allows them to lower the risk of their breeding stock and minimize the risk of producing affected dogs.
With this information, the breeder can plan matings that avoid producing any affected dogs by always selecting one parent that is normal.
Pedigrees are evaluated carefully to lessen the risk of doubling up on a carrier and potentially causing a situation that could produce affected dogs.
(Example from the pedigree: Half the sire's carrier risk is.0625 and half the dam's carrier risk is.0838, so the chance of producing an affected dog is.0625 x.0838 =.0052 or 0.52 %.)
CA is caused by an autosomal recessive gene, which means both parents must carry the gene to produce an affected dog.
If unknown carrier breeding stock have not produced affected dogs, it is because they have not been involved in matings to other carriers or produced confirmed affected dogs.
The lesson here is that the only dogs whom we can say are carriers, are those who have produced affected dogs, or are the offspring of affected dogs.
There is no test for carriers, or way to identify carriers of CA, unless they produce an affected dog, or are the offspring of an affected dog.
As long as these dogs are bred to clear dogs, they will not produce any affected dogs.

Not exact matches

Researchers have identified the gene mutation that causes NEwS, and a DNA test is now available that allows breeders to avoid producing affected puppies by never breeding two dogs to each other if they are both carriers of the abnormal gene.
«Single sex heartworm infections, host immune responses affecting the presence of circulating microfilariae and the administration of heartworm preventives can be factors which produce occult infections in dogs
Owners or adopters of non-purebred dogs can also help by sterilizing their pets before they become sexually mature to prevent any possibility of producing affected offspring.
CAV - 2 also produces pneumonia in 10 - 20 percent of the affected dogs.
The parents and full and half siblings of an affected dog should not be bred close on the pedigree that produced it and should be bred to mates that do not have a family history of iris coloboma.
Carrier dogs should only be mated to clear dogs so as to avoid producing BFJE affected puppies.
Definitely do not breed affected dogs, and do not repeat matings that produced EPI.
A simple autosomal recessive means that the condition can occur in either sex and that it is generally transmitted by what appear to be normal animals though the late onset of the condition can result in «affected» dogs producing the defect because they were used prior to their «affected» state being known.
Remove from a breeding program any dog or bitch that is known to have repeatedly produced any significant condition that affects the physical or mental soundness of the progeny.
To date we have received samples from 12 dogs known to have produced CHG affected puppies, what we call obligate carriers, and every one has come up as a carrier on the laboratory test.
If screening detects that a dog is predisposed to a genetic disease (or likely to produce affected offspring) and / or perhaps already in the early stages of the disease, then no breeding can take place under the scheme.
When a breeder becomes aware that he has produced an HD - affected dog, he should make that information openly available through having a formal screening done through a system that allows or requires open listing, by posting the information on his website, or by seeing that the report is submitted to ASHGI's IDASH Open Health Database.
Conversely we identify normal dogs to them with which they can continue their breeding programs secure in the knowledge that they won't produce CHG affected pups or more carriers.
These dogs also produce amyloid in organs such as the kidneys affecting their function.
If we have a dog that is a carrier for one or both disorders then we must breed to a clear dog to avoid producing any affected puppies.
Therefore, we only test puppies that we are holding on to longer as show prospects and since we have already taken the precautions in which dogs we have paired together before the breeding we will only be producing clear or carriers and therefore none of our puppies will ever be affected by these disorders specifically.
Her other mates were probably not carriers, so 50 % of the puppies were normal, 50 % were carriers, but no affected dogs were ever produced.
Make sure the parents of breeding stock have normal eyes, and have not produced any PRA affected dogs.4.
Not until she was bred to another carrier were affected dogs produced.
In order to avoid producing crd2 - affected offspring, at least one dog of any breeding pair should be homozygous Normal / Clear (See chart below).
This explains why Cyd was bred several times prior to being bred to Jordan and never produced a PRA affected dog.
It isn't uncommon for your dog to produce blood in their vomit or even blackened stools, indicating the possibility that the liver is being affected.
In order to avoid producing affected offspring, carriers of the rcd1b mutation should never be bred to other carriers or to affected dogs (see chart below).
I.e., in offspring produced by one affected and one unaffected parent the relative risk was 1.3 times higher compared to the risk in offspring produced by two unaffected dogs.
However, dogs with mild disease can produce severely affected offspring.
The dog has a coat with proper furnishings but can potentially produce offspring with Improper Coat if it is mated to another Carrier or to an IC affected dog.
In offspring produced by two affected dogs the relative risk was 1.4 times higher compared to offspring from the previously mentioned mating combination and 1.8 times higher compared to offspring produced by two unaffected dogs.
When several cells responsible for producing digestive enzymes are destroyed, digestion may be affected long term and affected dogs may develop exocrine pancreatic insufficiency.
When clinically normal dogs produce affected offspring, it strongly suggests the disease is inherited as a simple recessive (or potentially a polygenic — multiple gene) trait, and both parents carry one «bad» copy of the gene causing the disease.
A mildly affected dog may produce off - spring with severe lesions.
Only 3 of the affected dogs had an affected parent, and breedings between an affected and an unaffected parent could produce either all unaffected offspring or a mix of affected and unaffected offspring in the same litter.
Five litters (23 dogs) without affected dogs were born to matings between parents that had both been known to produce affected offspring.
This mode of inheritance means that one affected dog crossed with one normal dog will produce puppies of which half, on average, will have the disease.
It is important to never breed two dogs together that carry one or more copies of the mutation, in order to avoid producing offspring that are affected with BFJE.
Refrain from further use of any dog / bitch that has produced serious defects detrimental to the animal's well being, affecting normal functions or impairment of vita
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