In order to eliminate this mutation from breeding lines and to avoid the potential of
producing affected pups, breeding of known carriers to each other is not recommended.
DNA tests allow breeders to make use of healthy carriers with no risk of
producing affected pups.
If a pra affected dog is mated with a different breed which has clear eyes cert for their breed will
they produce affected pups?
If inheritance is complex, even more dogs might carry genes that could produce the disease if they happen to be mated with a dog that can «fill in the blanks» to
produce affected pups.
Because of the recessive nature of the NAD inheritance, the mutation can exist in breeding lines without detection for many generations until two carriers of the mutation
produce an affected pup.
The table below highlights in yellow the breedings that will NOT
produce affected pups.
«Carrier «s or «Affected «s bred to «Normal / Clear «s will never
produce affected pups.
Not exact matches
What were probably
affected pups produced a decade ago and intermittently since in different kennels around the country have been described to us.
With the DNA test CEA can easily be managed in your breeding program without fear of
producing more
affected pups.
Conversely we identify normal dogs to them with which they can continue their breeding programs secure in the knowledge that they won't
produce CHG
affected pups or more carriers.
All other breedings are at risk of
producing CD -
affected pups.
Properly identifying
affected dogs and, where possible, determining the genotype for relatives, is vital to prevent
producing more
affected pups.
With the aid of DNA testing, all dogs, even those carrying the crd3 mutation, can be bred with complete confidence that no crd3 -
affected pups will be
produced.
This table highlights in yellow the desirable breedings that will NOT
produce crd3 -
affected pups.
All other breedings are at risk of
producing crd3 -
affected pups.
Breeding untested dogs or breeding two carrier dogs puts you at risk of
producing PRA -
affected pups.