Sentences with phrase «producing gene disruptions»

In addition to genomic sequencing, the BDGP is 1) producing gene disruptions using P element - mediated mutagenesis on a scale unprecedented in metazoans; 2) characterizing the sequence and expression of cDNAs; and 3) developing informatics tools that support the experimental process, identify features of DNA sequence, and allow us to present up - to - date information about the annotated sequence to the research community.

Not exact matches

Through temporary disruption of these interactions, the scientists were able to produce Drosophila epilines characterized by different levels of PcG - dependent gene repression or activation.

If female fertility gene disruption occurred early in development rather than in the germline, the same system could produce a male - linked dominant sterile - daughter effect that would be less powerful but more readily modulated (Supplementary Fig. 10).

This happens when there is a mutation of the FGFR3 gene (the gene responsible for producing a protein that develops and maintains the growth of bone and brain tissue), which then causes disruptions in skeletal development.