His body wasn't
producing myostatin, a gene that inhibits muscular growth.
Not exact matches
If
myostatin does act systemically, the implication would be that local control of muscle growth can be influenced at least in part by
myostatin being
produced elsewhere in the body and that
myostatin functions precisely as a chalone, as originally hypothesized by Bullough [25], [26] for the control for tissue growth in general.
It is the flip - side of
myostatin, as increased follistatin blocks the activity of
myostatin: either increased follistatin or reduced
myostatin produce similar outcomes in animal studies, with treated individuals demonstrating increased muscle mass.
In mice, introducing a variant of PGC - 1
produces enhanced muscle growth, most likely via its interaction with
myostatin.