Not exact matches
In contrast, the biologic approach injects a genetically engineered protein designed to knock out a
tumor's ability to
produce new blood vessels, thereby cutting off its capacity to grow.
Their stem cell - like properties enable them to maintain a pool of cancer stem cells within the
tumor, as well as to
produce new mature
tumor cells.
One of the 43 began
producing a
new protein, which the researchers took to be an antibody to the
tumor antigen.
Lee's study results, which appear in the July 16, 2015 issue of Nature Communications, revealed
new understanding about how 14 -3-3 sigma — a cell cycle «controller» - regulates cancer metabolic programming, thus protecting healthy cells from turning into
tumor -
producing factories.
The
new study revealed that pancreatic cancer cells not only send signals that make macrophages
produce abnormal amounts of dectin - 1 surface receptors, but also that make
tumor cells themselves express high levels of galectin - 9.
In the
new study, the researchers used a combination of four different therapies to activate both of the immune system's two branches,
producing a coordinated attack that led to the complete disappearance of large, aggressive
tumors in mice.
In cancer, however, this process can
produce invasive and mobile cells that can pass through membranes and travel to distant sites, where they seed
new tumors.
While the general technique — eliminating
tumors with focused energy — is not
new, radiation oncologists, medical physicists, and scientists are combining a number of modern technologies for
producing significant breakthroughs in radiation therapy.
A careful balance exists where there are the same number of
new cells are
produced as there are dying off - and if this balance is disrupted, extra cells begin to replicate, undergo genetic changes, and it is these excess, mutated cells that gather together to form masses and
tumors.