Sentences with phrase «producing pancreas cells»

Stem cell scientist Sheng Ding has used his unique drug cocktails to turn skin cells into brain, heart, liver, and insulin - producing pancreas cells.

Using unique drug cocktails, stem cell scientist Sheng Ding, PhD, a senior investigator at the Gladstone Institutes, can transform fibroblasts (skin cells) into fully functional brain, heart, liver, and insulin - producing pancreas cells.

Gladstone scientist Dr. Sheng Ding has exposed more chameleon - like qualities of the human skin cell, using chemical cocktails to turn skin cells into fully functional brain, heart, liver, and insulin - producing pancreas cells.

To date, researchers have used human iPS cells to make cardiac cells that repaired heart damage in a pig and insulin - producing pancreas cells that reversed high blood sugar in mice.

«Diabetic mice on fasting - mimicking diet repair insulin - producing pancreas cells.»

Not exact matches

This type of diabetes strikes in the early teenage years and begins with the immune system destroying the cells in the pancreas that produce insulin, according to Patrick Holford, founder of the Institute for Optimum Nutrition in London.

It is often caused by the destruction of the insulin - producing cells of the pancreas resulting in an insulin deficiency.

Usually, the body's own immune system — which normally fights harmful bacteria and viruses — mistakenly destroys the insulin - producing (islet, or islets of Langerhans) cells in the pancreas.

If the tumor that Jobs had removed in 2004 had begun to break down prior to the surgery, White says, the tumor's dead cells could have released protease and lipase enzymes that may have damaged beta cells in the pancreas, which produce insulin.

Her pancreas produced insulin that unlocked her cells so the glucose could enter and produce the energy she needed to function.

A FAULTY internal clock in the cells in the pancreas that produce insulin could be behind type 2 diabetes — a condition in which the body is unable to produce or use insulin properly.

Over the past 15 years, the GFP gene has enabled scientists to watch a plethora of previously murky biological processes in action: how nerve cells develop in the brain, how insulin - producing beta cells form in the pancreas of an embryo, how proteins are transported within cells, and how cancer cells metastasize through the body.

People with diabetes can no longer regulate their blood sugar levels effectively via the hormone insulin, which is produced by beta cells in the pancreas.

By introducing caerulein to the pancreas we were able to generate new beta cells — the cells that produce insulin — potentially freeing patients from daily doses of insulin to manage their blood - sugar levels.»

Research in mice and human cells suggests that a fasting - mimicking diet may reprogram pancreas cells that are unable to produce insulin and enable them to repair themselves and start making it.

This leads to high blood glucose values; the function of the insulin - producing cells in the pancreas is also negatively influenced.

In the pancreas, pancreatic beta cells produce insulin, the hormone that provides fuel to the body's cells by transporting glucose.

In this type of diabetes, the body destroys insulin - producing cells in the pancreas, resulting in high blood glucose levels.

A chemical produced in the pancreas that prevented and even reversed Type 1 diabetes in mice had the same effect on human beta cells transplanted into mice, new research has found.

The four children also had more of the types of species that are known to trigger gut inflammation, a possible prelude to type - 1 diabetes, in which the body's immune system mistakenly produces antibodies that attack and destroy the beta cells of the pancreas that normally make insulin.

In those mice, but not in normal mice, they found that caerulein caused existing alpha cells in the pancreas to differentiate into insulin - producing beta cells.

The insulin these cells produced acted on blood sugar levels in the same way as insulin from the pancreas.

A new study by researchers at Sanford - Burnham Medical Research Institute (Sanford - Burnham) has found that a peptide called caerulein can convert existing cells in the pancreas into those cells destroyed in type 1 diabetes insulin - producing beta cells.

The disease commonly starts in childhood and causes the body's own immune system to attack and destroy the insulin - producing cells in the pancreas, leaving the patient dependent on life - long insulin injections.

At the very least, Domínguez - Bendala hopes that they could use BMP - 7 to convert the other 98 per cent of donor pancreas cells into beta cells, which, he estimates, could potentially provide enough insulin - producing cells to transplant into seven people.

Now, researchers have discovered that non-beta cells in the pancreas can be transformed into insulin - producing cells, merely by exposing them to a growth factor called BMP - 7.

In «Diabetic rats cured with their own stem cells ``, we report how researchers cured diabetic rats by turning brain stem cells extracted through the nose into insulin - producing cells in the pancreas.

In type 1 and late - stage type 2 diabetes, the pancreas loses insulin - producing beta cells, increasing instability in blood sugar levels.

Diabetes results from too few insulin - producing «beta cells» in the pancreas secreting too little insulin, the hormone required to keep blood sugar levels in the normal range.

Islet autoimmunity, detected by antibodies that appear when the immune system attacks the islet cells in the pancreas that produce insulin, is a precursor to type 1 diabetes.

In type 1 diabetes, the immune system attacks and destroys insulin - producing cells in the islets of the pancreas.

The overproduction could attack the insulin - producing cells of the pancreas and trigger diabetes, she wrote in the June 6 Journal of Proteome Research of the American Chemical Society.

In the case of type 1 diabetes, it destroys the insulin - producing cells in the pancreas, and in multiple sclerosis it strikes the central nervous system.

Type 1 diabetes hits when the body destroys insulin - producing cells in the pancreas.

Insulin - producing cells (yellow) produce the hormone insulin (green spheres) and are surrounded by other cells in the pancreas.

The mutant mice produced less insulin — the hormone made in the pancreas that helps cells burn sugar — and they were plump and diabetic, with high levels of glucose in their blood.

The most intriguing mutant type of mice were unusually thin; they generated more active osteocalcin, secreted more insulin, and produced many times more of the insulin - releasing cells in the pancreas.

The disease begins when a person's own antibodies attack the insulin - producing cells in the pancreas.

Douglas Melton, codirector of the Harvard Stem Cell Institute in Cambridge, Massachusetts, and his colleagues study both the stem cells that develop into the pancreas and its insulin - producing cells and the genes that guide those cells» development.

He and his collaborators found that three transcription factors, when targeted to the pancreas of a living mouse, converted fully formed, non-insulin-producing pancreatic cells into cells that were functionally identical to insulin - producing cells — no stem cells required.

The researchers used an adeno - associated viral (AAV) vector to deliver to the mouse pancreas two proteins, Pdx1 and MafA, which reprogrammed plentiful alpha cells into functional, insulin - producing beta cells.

When the pancreatic islets, small masses of cells in the pancreas that produce insulin, are exposed to high levels of nutrients — as is the case among people who eat a lot — they become inflamed.

He had to have his pancreas removed, and instead of throwing his gland away, we took it back to the lab and got maybe 50,000 to 100,000 of these insulin - producing cells.

Like the childhood form, the insulin - producing beta cells of the pancreas are destroyed by the body's own immune system.

These are organized in germ layers and are thus the origin of different tissue types, including the pancreas and its insulin - producing beta cells.

Diabetes is characterized by a dysfunction of the insulin - producing beta cells of the pancreas.

When they briefly exposed nestin - positive cells to a growth factor, the cells differentiated not only into neural cells but also into clusters that resemble the insulin - producing islets in the pancreas.

A number of radiotherapies that marry a small but potent amount of radioactive material and a targeted molecular compound have been gaining traction as progressive treatments for malignant NETs, which can develop wherever nerve cells and hormone - producing endocrine cells are present (e.g., gastrointestinal tract, pancreas, lungs, thyroid).

A ONE - OFF treatment for diabetes is a step closer thanks to a better understanding of how human liver cells can be transformed into something like the beta cells that produce insulin in a healthy pancreas.

* In type 1 diabetes, the insulin - producing cells in the Langerhans islets of the pancreas are destroyed because they are attacked by the body's immune system (formation of islet autoantibodies against structures of the beta cells).