In addition, because many of the deadlier spider venoms produce their toxic effects by overstimulating
the production of brain signaling molecules, this research may uncover novel tools for neuroscience research.
Not exact matches
Nerves that lead from the nipple and areola send a
signal to the
brain to stimulate the release
of breast milk and the
production of more milk.
Your
brain will send
signals telling that
production of melatonin should be enhanced.
Once such mutation prevents the
production of an enzyme needed to break down retinol, a form
of vitamin A, into a substance that photoreceptors need to detect light and send
signals to the
brain.
GLP - 1 receptors are also found in the
brain, and prior research has shown that activating them can boost the function
of dopamine connections, act as an anti-inflammatory, improve energy
production, and switch on cell survival
signals.
In the
brain, cytokines can disrupt the
production and release
of several important
signaling chemicals, including serotonin, dopamine and glutamate, which help control emotion, appetite, sleep, learning and memory.
The researchers speculated that
brain cells might be particularly reliant on their mitochondria to power the
production and recycling
of the chemical
signals they use to transmit information.
The anti-apoptotic effect
of BES was dependent on the activation
of the PI3K / Akt
signaling cascade and an increase in
brain - derived neurotrophic factor (BDNF)
production.
Endowed with the power to control the activity
of other genes, GTF2I might regulate
signal pathways determining the structure and function
of the
brain or the
production of neurohormones such as vasopressin and oxytoxin.
These results suggest that CCHa2 and CCHa2 - R functionally connect peripheral tissues with the
brain, and that CCHa2 / CCHa2 - R
signaling coordinates the animal's growth with its nutritional conditions by regulating its
production of insulin - like peptides.
Although no
signaling molecules that act downstream
of the Slif / TOR pathway have been identified yet, these fat body - derived
signals ultimately regulate the
production of insulin - like peptides (Drosophila insulin - like peptides; Dilps) secreted from the
brain [10][9].
This medication is prescribed based on the theory that anxiety is a extraverted version
of depression, and that both involve disturbances in the
production and
signalling of serotonin, the «happy hormone», in the
brain.
And this will cause the
brain to
signal the same
production of insulin as when you eat sugar.
The leading theory
of depression for decades, the Monoamine Theory, states that in people who suffer from depression, there is an imbalance in serotonin
production and
signalling in the
brain — a «serotonin deficiency» — which SSRI medication corrects.
This important vitamin is involved in the
production of neurotransmitters, chemicals that help
signals move from one
brain cell to another.
The
brain takes its
signals from the amount
of circulating cortisol — not circulating aldosterone — so high cortisol tends to lower the
brain's ACTH
production, which in turn decreases aldosterone secretion, leading to lower blood pressure.
Aβ is believed to penetrate neuronal plasma membranes, where it leads to lipid peroxidation.10 It has also been implicated in deactivating a subunit
of the pyruvate dehydrogenase complex, thereby inhibiting conversion
of pyruvate to acetyl CoA and the eventual
production of cellular energy as ATP.32 Another way Aβ affects glucose metabolism in the
brain is that fragments
of Aβ disrupt insulin
signaling by binding to neuronal synapses, which alters their shape and function.15, 38 Insulin receptors are abundant at synapses, so if the integrity
of the synapse itself has been compromised, the receptors won't function effectively.
«It is strongly suggested that impaired insulin
production and
signaling in AD
brain... cause
brain mitochondrial dysfunction due to severe impairment
of glucose or glycogen metabolism.»
These include insoluble extracellular plaques made
of beta - amyloid peptide (Aβ); intracellular neurofibrillary tangles (NFTs) resulting from the hyperphosphorylation
of tau (a microtubule - associated protein); loss
of hippocampal neurons; a decrease in
production of brain acetylcholine; and a marked decline in glucose usage in regions
of the
brain associated with memory and learning.5,11,20 - 22 All
of these changes can be logically explained as the sequelae resulting from long - term dysregulation
of insulin
signaling and glucose metabolism.
Bitter herbs stimulate receptors on the tongue that
signal the
brain to increase the
production of digestive enzymes and saliva.
Excess estrogen also
signal to our
brain to limit the
production of testosterone.
These foods lead to spikes in blood sugar and the
production of excitotoxins — a reaction that causes your gut's nerve cells to send a
signal to your
brain that sounds an alarm, putting you into fight or flight mode.
DHA is active in the membrane
of ion channels in the
brain, making it easier for them to change shape and transmit electrical
signals, and is involved in serotonin metabolism (reduced serotonin
production and / or activity is a key factor in depression).