Sentences with phrase «professor in the gene expression»

«Telomerase is a unique protein - RNA complex where the protein subunit uses its RNA component as a template to add identical fragments of DNA to the end of chromosomes,» said Emmanuel Skordalakes, Ph.D., associate professor in the Gene Expression and Regulation program of Wistar's NCI - designated Cancer Center.

Either p53 itself is mutated or there is a problem with one of the proteins that regulate p53's activity,» says the study's leader Geoffrey M. Wahl, Ph.D., a professor in the Gene Expression Laboratory.

The other is Geoffrey Wahl, a professor in the Gene Expression Laboratory.

«What we're seeing may not only be happening in limbs, but the action of these two families of growth factors could be very important for the genesis of a wide range of organs in the body,» said Juan Carlos Izpisúa Belmonte, a professor in the Gene Expression Laboratory at Salk and the principal author of the Cell paper.

«Having a very efficient and practical way of generating patient - specific stem cells, which unlike human embryonic stem cells, wouldn't be rejected by the patient's immune system after transplantation brings us a step closer to the clinical application of stem cell therapy,» says Belmonte, PhD., a professor in the Gene Expression Laboratory and director of the Center of Regenerative Medicine in Barcelona, Spain.

Not exact matches

Scientists at Southern Methodist University, led by Professor and Chair of Biological Sciences Santosh D'Mello, have used RNA - Seq to conduct transcriptome profiling of gene expression changes in dying neurons.

We wanted to understand what types of differences are always there, what is causing them, and what they mean,» says Juan Carlos Izpisua Belmonte, a professor in Salk's Gene Expression Laboratory and co-senior author, with Kelly Frazer of the University of California, San Diego, on the new paper, which was published in Cell Stem Cell in April 2017.

P. Read Montague, professor of neuroscience at Baylor College of Medicine, says, «In a sense, every measurement that you make in neuroscience — electrophysiological, optical, gene expression, and so on — is imaginIn a sense, every measurement that you make in neuroscience — electrophysiological, optical, gene expression, and so on — is imaginin neuroscience — electrophysiological, optical, gene expression, and so on — is imaging.

Sankar Ghosh, professor of immunobiology at Yale University, explores the regulation of gene expression in developing and differentiating lymphocytes.

According to Izpisúa Belmonte, who is also a professor at the gene expression laboratories of the Salk Institute for Biological Studies in San Diego, California, CMRB aims to become «a research centre of excellence in south Europe in the line of world - recognized institutions such as the Salk or the Whitehead institutes, where both pre - and postdoctoral researchers receive multidisciplinary training of the highest quality» in stem cell biology and cell regeneration.

«It is exciting to find a correlation between brain circuitry and gene expression by combining high quality data from these two large - scale projects,» says David Van Essen, Ph.D., professor at Washington University in St. Louis and a leader of the Human Connectome Project.

«We discovered that beta blockers largely reverse the pathological pattern of gene expression observed in heart failure,» said Faculty of Science Professor John McDermott, who led the research, along with York U collaborators Professor Gary Sweeney and Professor Jorg Grigull.

«The number of protein functions that are currently targeted by drugs is incredibly small compared to the total number of protein interactions that could be targeted for therapeutic benefit,» says Geoffrey Wahl, a professor in Salk's Gene Expression Laboratory.

«The use of a radiofrequency - driven magnetic field is a big advance in remote gene expression because it is non-invasive and easily adaptable,» says Dordick, who is Howard P. Isermann Professor of Chemical and Biological Engineering and vice president of research at Rensselaer.

«Margery's experiments showed that the NS1 protein can alter expression of Hedgehog target genes on its own, without other viral proteins,» said Bier, professor and newly named holder of the Tata Chancellor's Endowed Professorship in Cell and Developmental Biology.

In this study, a team led by Panos N. Papapanou, DDS, PhD, professor and chair of oral, diagnostic and rehabilitation sciences at the College of Dental Medicine at CUMC, «reverse - engineered» the gene expression data to build a map of the genetic interactions that lead to periodontitis and identify individual genes that appear to have the most influence on the disease.

«We found that zinc oxide (ZnO) nanoparticles at doses that are relevant to what you might normally eat in a meal or a day can change the way that your intestine absorbs nutrients or your intestinal cell gene and protein expression,» said Gretchen Mahler, associate professor of bioengineering.

Douglas Thomas, associate professor of medicinal chemistry and pharmacognosy at UIC, and co-workers discovered that nitric oxide plays an important role in epigenetics — heritable alterations in gene expression caused by mechanisms other than changes in DNA sequence.

A new function now described for the protein dDsk2 by the team headed by Ferran Azorín, group leader at the Institute for Research in Biomedicine (IRB Barcelona) and CSIC research professor, links ubiquitin receptors for the first time with the regulation of gene expression.

«The bugs are somehow driving gene expression in the host through alteration of the epigenome,» explains John Denu, a UW - Madison professor of biomolecular chemistry and a senior researcher at the Wisconsin Institute for Discovery, and a co-author of the new study.

«By looking comprehensively at gene expression within cells, we can now spot numerous important differences in complex tissues like the brain that are invisible today,» said George Church, Ph.D., a Core Faculty member at the Wyss Institute and Professor of Genetics at Harvard Medical School.

«We provide a proof - of - principle for how to make and maintain unlimited numbers of precursor kidney cells,» says Juan Carlos Izpisua Belmonte, professor in Salk's Gene Expression Laboratory.

Although we have long known that this signal strongly inhibits protein synthesis in general, during hemoglobin gene expression it first plays its indispensable, positive role before being turned off promptly to allow for massive hemoglobin formation needed for breathing,» said Prof. Raymond Kaempfer, the Dr. Philip M. Marcus Professor of Molecular Biology and Cancer Research at the Hebrew University of Jerusalem.

«Because there are currently no effective drugs for liver fibrosis, we believe our findings would open a new door for treatment,» says senior author Ronald M. Evans, a professor in Salk's Gene Expression Laboratory and lead researcher in the Institute's new Helmsley Center for Genomic Medicine.

Working in mice that were put on high - fat diets to model diabetes, «we demonstrated that obesity increases the expression of pro-inflammatory genes in abdominal fat, but not in other organs such as the liver or muscle, nor in subcutaneous fat,» says Jongsoon Lee, PhD, Assistant Investigator in Joslin's Section on Pathophysiology and Molecular Pharmacology and Assistant Professor of Medicine at Harvard Medical School.

Their synergy with vitamin D to increase CAMP gene expression was significant and intriguing,» said Adrian Gombart, an LPI principal investigator and associate professor in the OSU College of Science.

«We observed small but significant changes in the gene expressions between normal and diabetic corneas,» said Mehrnoosh Saghizadeh Ghiam, PhD, assistant professor of biomedical sciences and neurosurgery, a researcher in the Regenerative Medicine Institute Eye Program and the lead author of the study published in the journal PLOS ONE.

To work out the genetic basis, Duke University postdoctoral associate Bob Fitak and biology professor Sönke Johnsen and colleagues investigated changes in gene expression that take place across the rainbow trout genome when the animal's magnetic sense is disrupted.

«It is important to understand how nucleosomes are moved, ejected or restructured, as this will affect the accessibility of promoter DNA, which in turn influences the expression of the corresponding genes,» explains David Shore, professor at the Department of Molecular Biology of the Faculty of Science at UNIGE.

«The bugs are somehow driving gene expression in the host through alteration of the epigenome,» explains John Denu, a UW — Madison professor of biomolecular chemistry and a senior researcher at the Wisconsin Institute for Discovery, and a co-author of the new study.

A research team, led by Chao Cheng, Ph.D., Assistant Professor in the Department of Genetics at The Geisel School of Medicine at Dartmouth, used gene expression data from breast cancer patients to computationally infer the presence of different types of immune cells.

Professor Dermitzakis» research focuses on the genetic basis of regulatory variation and gene expression variation in the human genome, the processes that govern non-coding DNA evolution.

Wahl, a professor in Salk's Gene Expression...

Researchers who contributed to the work include staff scientist Mathias Leblanc, Ph.D. and postdoctoral researcher Mark Wade, Ph.D., in the Gene Expression Laboratory and professor Aart G. Jochemsen, Ph.D. at the Leiden University Medical Center, The Netherlands.

Wahl, a professor in Salk's Gene Expression Laboratory, will receive $ 7.9 million over a seven - year period to further his cancer research.

«This is the most comprehensive effort to do a genomic comparison between humans and mice at this level, including the regulatory elements and gene expression,» said Feng Yue, an assistant professor in the department of biochemistry and molecular biology at Penn State College of Medicine.

Joshua P. Martin, Ph.D., assistant professor of biology, Colby College was the mentor and the research topic was RNA sequencing and analysis of gene expression in Tenodera sinensis

Researchers in the laboratory of Mikhail Shapiro, assistant professor of chemical engineering and Heritage Medical Research Institute Investigator, have invented a new method to link magnetic resonance imaging (MRI) signals to gene expression in cells — including tumor cells — in living tissues.

«Stem cells in a healthy developing embryo have a GPS system to alert them about their position in the organ,» says Geoffrey Wahl, a professor in Salk's Gene Expression Laboratory, who led the research.

«When we looked at gene expression, we found fairly small changes in 65 million years of the macaque, orangutan, and chimpanzee evolution,» said study author Yoav Gilad, PhD, assistant professor of human genetics at the University of Chicago, «followed by rapid change, along the five million years of the human lineage, that was concentrated on these specific groups of genes.

«The ability to direct a gene to a specific cell type and prevent expression in other cell types is a powerful new tool that allows us to bypass one of the most troubling safety concerns facing gene therapy,» said Michael Parmacek, MD, assistant professor of medicine at the University of Chicago and director of the study.

Two years later, Vijay joined the La Jolla Institute for Allergy and Immunology as an adjunct assistant professor in the Division of Signaling and Gene Expression.

Tumor - suppressor connects with histone protein to hinder gene expression (4/10/2014) Dr. Hong Wen, an Assistant Professor in Xiaobing Shi's lab found that the protein ZMYND11 recognizes a special mark on another protein that helps package and protect DNA, the histone variant H3.3.

This appears in the latest study from the lab of Rugang Zhang, Ph.D., deputy director of The Wistar Institute Cancer Center, professor and co-program leader of the Gene Expression and Regulation Program.

Moreover, because trans - Tango works by instigating the expression of genes in connected pairs of neurons, it also has the potential to enable scientists to control circuit functions, says senior and corresponding author Gilad Barnea, PhD, an associate professor of neuroscience who began looking for a precise, reliable, and general way to visualize neural connections two decades ago.

The theory proposed by Professor Khavinson is based on the underlying assumption that changes in gene expression result in decreased protein synthesis, eventually leading to aging and the development of diseases.