Zonari E, Desantis G, Petrillo C, Boccalatte FE, Lidonnici MR, Kajaste - Rudnitski A, Aiuti A, Ferrari G, Naldini L, Gentner B. Efficient ex vivo engineering and expansion of highly purified human hematopoietic stem and
progenitor cell populations for gene therapy.
Not exact matches
For that, they quantified how 85 nanoparticles delivered DNA barcodes to eight
cell populations in the spleen, and found that
cell types derived from myeloid
progenitors tended to be targeted by similar nanoparticles.
Researchers have identified a
population of «
progenitor»
cells in the skin that are solely responsible
for the generation and maintenance of touch - sensing Merkel
cells.
Discovered a series of signaling events beginning with the morphogen Sonic hedgehog (Shh) that are essential
for guiding a
population of late cardiac
progenitor cells in the outflow tract of the heart.
This two - volume reference integrates this exciting area of biology, combining the prerequisites
for a general understanding of adult and embryonic stem
cells, the tools, methods, and experimental protocols needed to study and characterize stem
cells and
progenitor populations, as well as a presentation by the world's experts of what is currently known about each specific organ system.
Based on previous protocols [5, 6] they have now created a 3D protocol
for chondrogenic lineage differentiation via the generation of a putative chondrogenic
progenitor cell population, and have found that using this protocol C - iPSCs can be readily differentiated into cartilage in a manner comparable to that of mature chondrocytes [7].
The researchers suggest that a single expandable embryonic lung
progenitor population with broader developmental competence may eventually be used as an alternative
for region - restricted adult tissue stem
cells in regenerative medicine.
The success of marker - based approaches
for dissecting haematopoiesis in mouse and human is reliant on the presence of well - defined
cell surface markers specific
for diverse
progenitor populations.