Sentences with phrase «progenitor cell proliferation»

They ascertained that a combination of WNT, FGF, BMP and LIF, each at a low concentration, allowed for peak progenitor cell proliferation.

Not exact matches

Transient Silencing of 14 -3-3sigma promotes proliferation of p63 - positive progenitor cells isolated from human breastmilk in mammary epithelial cell culture.

They demonstrated how ANG stimulates proliferation of myeloid progenitor cells.

«We knew that ANG was involved in promoting cell growth so it was not unexpected to find that ANG stimulates proliferation of myeloid progenitor cells,» said Guo - fu Hu, PhD, Investigator in the Molecular Oncology Research Institute at Tufts Medical Center, and the paper's senior author.

In the paper, the researchers show for the first time that ANG simultaneously reduces proliferation of stem cells and promotes proliferation of myeloid progenitor cells that give rise to mature myeloid cells.

After four days, harmine led to a 70 % increase in proliferation of human neural progenitor cells.

Dr. Alicia Melendez, a biologist at Queens College, City University of New York (CUNY), and her colleagues report in Current Biology that autophagy is important for the proliferation of stem cells, specifically for promoting the cell cycle of stem cell progenitors.

This antibody activates an integrin on the cell surface of basal progenitors and thus stimulates their proliferation,» explains Denise Stenzel, who headed the experiments.

Using mice deficient in Del - 1, they found that the protein promotes proliferation and differentiation of hematopoetic stem cells, sending more of these progenitor cells down a path toward becoming myeloid cells, such as macrophages and neutrophils, rather than lymphocytes, such as T cells and B cells.

A normally functioning adult human brain has the ability to partially replenish or repair itself through neurogenesis, the proliferation and development of adult neural progenitor / stem cells (aNPCs) into new nerve cells.

MicroRNA - 195 regulates proliferation, migration, angiogenesis and autophagy of endothelial progenitor cells by targeting GABARAPL1.

MicroRNA - 138 inhibits hypoxia - induced proliferation of endothelial progenitor cells via inhibition of HIF - 1a - mediated MAPK and AKT signaling.

Akt increases sox2 expression in adult hippocampal neural progenitor cells, but increased sox2 does not promote proliferation.

Progesterone increases rat neural progenitor cell cycle gene expression and proliferation via extracellularly regulated kinase and progesterone receptor membrane components 1 and 2.

Effects of dehydroepiandrosterone on proliferation and differentiation of chromaffin progenitor cells.

The neurosteroid allopregnanolone promotes proliferation of rodent and human neural progenitor cells and regulates cell - cycle gene and protein expression.

Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed death 1 pathway.

Expression of the melanoma cell adhesion molecule in human mesenchymal stromal cells regulates proliferation, differentiation, and maintenance of hematopoietic stem and progenitor cells.

Electrical stimulation of the medullary pyramid promotes proliferation and differentiation of oligodendrocyte progenitor cells in the corticospinal tract of the adult rat.

To this end, we are focusing on two aspects of β - cell regeneration: enhancing β - cell proliferation in vivo and stimulating the differentiation of new β - cells from endogenous progenitors in the pancreas.

The FLT3 - signaling pathway controls cell proliferation and survival, particularly of hematopoietic progenitor cells.

Mutations may bias progenitor cell fate towards proliferation.

Social isolation prevents exercise - induced proliferation of hippocampal progenitor cells in female rats.

Manuscripts that increase our understanding of the processes through which stem cells and progenitors differentiate into committed progeny, the commitment cell death programs such as apoptosis and necrosis, aging, and the transition between proliferation and cell cycle arrest are welcome.

Dual actions of Meis1 inhibit erythroid progenitor development and sustain general hematopoietic cell proliferation.

Possible modes of hierarchy alteration are suggested as increased self - renewal (a), dedifferentiation of early progenitor cells (b), and blocked proliferation (c) of ER - α — positive and negative tumors.

BETHESDA, MD — Infection with Zika virus disrupts fetal brain development by interfering with the proliferation of human neural progenitor cells (hNPCs), a type of cell that drives neurodevelopment and proliferates into brain and nervous system cells, according to research presented at the American Society of Human Genetics (ASHG) 2016 Annual Meeting in Vancouver, B.C.

Immunocytochemical staining for Ki67 (cell proliferation marker), Sox2 (neural stem cell marker), Olig2 (progenitor cell marker), and GFAP (glial fibrillary acidic protein, a marker for differentiated astrocytes) captured by confocal microscopy imaging.