Sentences with phrase «progenitor cell stage»

Not exact matches

In the bone marrow, blood stem cells give rise to a large variety of mature blood cells via progenitor cells at various stages of maturation.

In a series of experiments reported in PLOS ONE in August, the Tufts researchers showed that exosomes from PC12 cells (neuron - like progenitor cells derived from rats) at various stages of their own differentiation could, in turn, cause hMSCs to become neuron - like cells.

Bacterial spores store information about the individual growth history of their progenitor cells, thus retaining a «memory» that links the different stages of the bacterial life cycle.

Hwang and his team harvested stem cells — the self - renewing progenitors of all cells in the body — from cloned early - stage embryos made by slipping the nucleus of a skin cell into a nucleus - free egg.

Nephron progenitor cells (NPCs), at least in humans, normally only exist during a brief stage of embryonic development.

Wang and other colleagues previously discovered a molecule (called compound C) that converts stem cells into «neural progenitor cells,» an early stage in the cells» development into neurons.

At a later stage, mimicking the second trimester, Zika still preferentially infected neural progenitor cells, but it also affected some neurons.

Stage - specific embryonic antigen - 4 is not a marker for chondrogenic and osteogenic potential in cultured chondrocytes and mesenchymal progenitor cells.

In the study, which was conducted in collaboration with researchers at UC San Francisco and published today in the Journal of Neuroscience, scientists transplanted inhibitory neuron progenitors — early - stage brain cells that have the capacity to develop into mature inhibitory neurons — into two mouse models of Alzheimer's disease, apoE4 or apoE4 with accumulation of amyloid beta, another major contributor to Alzheimer's.

This visualization shows tightly - packed DNA in a mouse cell's nucleus at different stages of development, seen here in a semi-triangular form as a mature nerve cell; in a roundish shape as a multipotent stem cell; in a more oval form as a neuronal progenitor; and as a more fragmented structure that shows how removing a specialized binding protein (HP1β knockout) affects the structure of the DNA - packing material, called heterochromatin, in a mature neuron.

These renderings show a tightly packed form of DNA called heterochromatin as it exists in a mouse cell's nucleus at different stages of cell development: a multipotent stem cell (left), a neuronal progenitor (middle), and a mature nerve cell (right).

By examining fetal mouse livers, which are rich sources of red blood cells and their progenitors, Wenqian Hu screened the various stages of red blood cell development for the presence of lncRNAs.

We have previously reported that our 26 - d protocol closely recapitulates key stages of biliary development, starting with the differentiation of hPSCs into endoderm and subsequently into foregut progenitor (FP) cells, followed by the generation of hepatoblasts (HBs), cholangiocyte progenitors (CPs) expressing early biliary markers and mature CLCs displaying cholangiocyte functionality.

Supported by a CIRM translational grant, scientists in Huang's laboratory are using human stem cells to create inhibitory neuron progenitors — early - stage brain cells that can develop into mature inhibitory neurons.

These cells return to a precursor stage following their spontaneous fusion with transplanted haematopoietic stem and progenitor cells in damaged retinas.