Sentences with phrase «progenitor cells in the bone marrow»

We also analyzed the hematopoietic stem cells and various progenitor cells in the bone marrow.

Not exact matches

In the bone marrow, blood stem cells give rise to a large variety of mature blood cells via progenitor cells at various stages of maturation.

«Proper blood cell production is dependent on functioning hematopoietic stem and progenitor cells that are destroyed during conditioning procedures for transplantation or following bone marrow injury,» said the study's first author Kevin A. Goncalves, who performed this research as part of his PhD studies in cellular and molecular physiology at the Sackler School.

They may arise from either embryonic progenitors or bone marrow cells in adults.

By the 1970s researchers had recognized another type of progenitor cell in the adult bone marrow, which they named the mesenchymal stem cell.

A novel role for PECAM - 1 (CD31) in regulating haematopoietic progenitor cell compartmentalization between the peripheral blood and bone marrow.

Ovine bone - and marrow - derived progenitor cells and their potential for scaffold - based bone tissue engineering applications in vitro and in vivo.

Furthermore, these potentials are expanded by the notion that MSCs can exert functions other than those classically attributed to stem or progenitor cells, including establishment and support of the hematopoietic microenvironment in vivo, as observed for bone marrow derived MSCs.

Bone marrow CD169 + macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche.

Osteogenic induction of human bone marrow - derived mesenchymal progenitor cells in novel synthetic polymer - hydrogel matrices.

This VCAM - 1 - VLA - 4 interaction between bone marrow stromal cells and bone marrow progenitor cells helps to retain the progenitor cells in the bone niche.

Adult stem / progenitor cells are present in many organs and tissues, e.g., bone marrow, teeth, heart, gut, kidney and liver, and remain quiescent for long period of time until activated by a disease or injury trigger.

In Neu1 - deficient mice the excessive lysosomal exocytosis results in cleavage of VCAM - 1, loss of bone marrow progenitor cells from the bone niche and the onset of spleenic hematopoiesiIn Neu1 - deficient mice the excessive lysosomal exocytosis results in cleavage of VCAM - 1, loss of bone marrow progenitor cells from the bone niche and the onset of spleenic hematopoiesiin cleavage of VCAM - 1, loss of bone marrow progenitor cells from the bone niche and the onset of spleenic hematopoiesis.

Writing in Journal of Immunology, lead author and BSI member, Professor Graham Anderson explains, «Post-transplantation, T - cell progenitors derived from the bone marrow transplant can struggle to enter the thymus, as if the doorway to the thymus is closed.

They found that Lymphotoxin β receptor, a cell surface molecule, controls the entry of T - cell progenitors to the thymus, both in a healthy state and during immune recovery following bone - marrow transplantation.