Sentences with phrase «progression of these cancers»

«By studying the ways different proteins like keratin dynamically change within a cell, we can better understand the progression of cancers and other diseases,» they say.

«Unfortunately, most patients in this trial still experienced a progression of their cancer, demonstrating that we still have a lot of work to do.

But it is one of the first to specifically address how obesity promotes progression of these cancers in young adults.

As prostate cancer progresses, tumor cells may infiltrate this periprostatic adipose tissue: this is a key step in the progression of this cancer, as it signals locally advanced disease (where the cancer can progress to nearby organs).

It is believed that epigenetics play a huge role in the development and progression of cancer.

«However, patients eventually experience progression of cancer on this treatment, highlighting the need for additional therapies.

Meanwhile, cancer genome projects have yielded unprecedented insights into the cellular signaling pathways that drive the development and progression of cancer — information that has led to effective therapies tailored for individual patients.

These are aimed specifically at pathways involved in either the initiation and progression of cancer or its resistance to conventional drugs.

Among patients with advanced non-small cell lung cancer without a mutation of a certain gene (EGFR), conventional chemotherapy, compared with treatment using epidermal growth factor receptor tyrosine kinase inhibitors, was associated with improvement in survival without progression of the cancer, but not with overall survival, according to a study in the April 9 issue of JAMA.

Thus, the metabolic changes associated with oncogenesis may affect the epigenetic machinery, creating a feedback loop that synergistically promotes the progression of cancer.

This is important, he added, because this technique is increasingly used for classifying diseases and their subtypes, understanding gene expression changes during development and tracking the progression of cancer.

We can repeat liquid biopsies to monitor the progression of the cancer.

Through the study, researchers were also able to pinpoint three different brain changes caused by the progression of cancer and the drugs used in treatment.

«We are testing whether antioxidants applied directly to malignant melanoma cells in mice hasten the progression of cancer in the same way as their dietary counterparts,» Professor Bergö says.

«We have demonstrated that antioxidants promote the progression of cancer in at least two different ways,» Professor Bergö says.

Dr. Mehta says the cognitive decline may have stemmed from unrecognized progression of the cancer, masked by the use of bevacizumab, or neurotoxicity related to the bevacizumab.

He notes this link seems to be «really key to the progression of this cancer.»

Moffitt researchers want to develop a fast, cost - effective blood test that can accurately differentiate low - risk IPMNs that can be monitored from high - risk IPMNs that need to be surgically removed by studying microRNAs (miRNAs), a class of small molecules that regulate key genes involved in the development and progression of cancer.

«The progression of cancer to the metastatic stage represents a pivotal event that influences patient outcomes and the therapeutic options available to patients,» said senior author Pandolfi.

The Center for Environmental and Molecular Carcinogenesis (CEMC) provides state - of - the - art technologies and an intellectual framework to foster multidisciplinary research into the environmental, genetic and epigenetic factors that influence the initiation and progression of cancer.

The team found that 24 to 48 hours after the nanoparticles were administered, they had localized in the tumor tissues and released their drug cargo, and the drug had had the intended biological effects of inhibiting two proteins that are involved in the progression of the cancer.

In 2007, he joined Columbia University as a post-doc, where he developed network - based computational approaches aimed at identifying key drivers of initiation and progression of cancer, as well as mechanisms of therapeutic response and drug resistance.

Radiation therapy slows the progression of cancer growth.

Kancera AB is a biotechnology company that focuses on the development and sale of drug candidates that have the potential to cure or stop the progression of cancer.

Establishing the role of cigarette smoke in progression of cancer will not only produce the necessary evidence for implementing smoking cessation interventions but may also help to identify cellular mechanisms for therapeutic targeting.

In a life table model, assuming that these observations arose from a causal relation, we estimated the benefits of cessation to be substantial; the benefits on all cause mortality seem likely to be mainly due to reduced progression of cancer rather than prevention of cardiorespiratory disease, but no studies reported cancer specific death rates to confirm this.

Epithelial - mesenchymal transition (EMT) contributes to the progression of cancer through enhanced invasion and stem - like properties of cancer cells.

The fact that the risk elevation was apparent directly after cancer diagnosis, and decreased in magnitude over time, supports the conclusion that the risk increase may be traced to the diagnosis itself rather than the emotional or physical suffering related to progression of the cancer or to its treatment.

Deep read counts for these mutations in each sample revealed some interesting stories about the progression of the cancer from tumor to metastasis.

The epidermal growth factor receptor (EGFR) pathway is a complex signaling cascade that is involved in the development and progression of cancer.

They will use the virus to cause mutations in the genes — a process called mutagenesis screening — to find out which mutations result in progression of the cancer.

Remember, inflammation makes the immune system less effective in doing its job, and a less effective immune system leads to progression of cancer cells!

Another benefit, and perhaps the most important for cancer patients, is that EDTA binds with and removes from the body the excessive free radicals that many experts attribute to the development and progression of cancer.

Dr. Greger, Assuming one eats a strictly plant based diet, is there an optimal amount of total dietary fat for preventing cancer or slowing the progression of cancer?

A pro-inflammatory state is known to be an important contributing factor in both the development and progression of cancer.

Being rich in antioxidants, it can also reduce inflammation, which can help suppress the progression of cancer.

Within one week, the growth, spread and progression of cancer in both patients was halted by the diet.

She describes OMS as «a cluster of nutritional and metabolic factors that can influence the growth and progression of cancer.»

Another one of natures super foods, broccoli is not only high in vitamin A but also contains a compound that has the ability to work on a genetic level to «switch off» cancer genes, AND to hinder the progression of cancer.

Supplementing 20,000 IU of Vitamin D3 daily may be an effective therapy to inhibit the progression of cancer and decrease systemic inflammation.

To be perfectly clear, although a majority of healthcare providers tout the «importance» of conventional care, there is little evidence that undergoing these harmful procedures can actually halt or even slow the progression of cancer cells.

Adjunctive chemotherapy and / or radiation may also be given depending on the severity and progression of the cancer at time of diagnosis, and / or whether dog owners allow amputation.

Progression of Cancer in a Cat with Mammary Cancer HiI have a question about the speed of cat mammary cancer progression.

We will thoroughly investigate your case with expert medical witnesses to ascertain whether the misdiagnosis caused a sufficient delay which resulted in the metastatic progression of the cancer to other parts of the body or some other harm that would have otherwise been treatable.

Not exact matches

But a late - stage clinical trial called CheckMate - 026 for the drug failed to meet its primary goal of halting cancer progression in advanced, untreated patients whose tumors consisted of at least 5 % PD - L1.

That's not just because of Opdivo's failure — last month, Keytruda was shown to be better than standard chemotherapy in untreated advanced lung cancer patients with high levels of the PD - L1 protein, both stopping cancer progression and extending patients» lives.

The technology measures the stage of disease, rate of progression of disease, drug efficacy, and drug toxicity in several cancers and Alzheimer's disease.

The biotech specialist said that its updated phase 2 data in a study of its poziotinib candidate treatment for non-small cell lung cancer resulted in a preliminary confirmed objective response rate and potential progression - free survival benefit in patients with the EGFR Exon 20 Mutant form of the disease.

In the area of cancer progression, we have seen what researchers refer to «anti-tumor» activity following consumption of mushroom extracts by rats and mice, particularly with respect to breast cancers.

It offers cardio protection, it helps lower bad cholesterol, it may help prevent the progression of multiple sclerosis, it has the ability to regenerate brain cells after a stroke, it has the ability to cross the blood - brain barrier to potentially ward off Alzheimer's disease, apparently it's good at wiping amyloid plaque from the brain (which studies haves linked to Alzheimer's), it may help to prevent certain types of cancer, and studies have shown that it inhibits cancer cell growth and metastases (meaning it keeps cancer from spreading).